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Target Organs and Levels of Evidence for TR-149

Bioassay of N,N'-Diethylthiourea for Possible Carcinogenicity (CASRN 105-55-5)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
N,N'-Diethylthiourea
105-55-5
08/31/1978Corrosion inhibitor; vulcanizationDosed-Feed
R: 0,125,250, M: 0,250,500 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: CARCINOMA
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Thyroid Gland Follicular Cell: ADENOMA OR CARCINOMA
Male Mice: Negative
Female Mice: Negative