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Target Organs and Levels of Evidence for TR-194

Bioassay of Selenium Sulfide (Gavage) for Possible Carcinogenicity (CASRN 7446-34-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Selenium sulfide
7446-34-6
05/01/1979Antidandruff shampoo, glass, electronics, rubber, in treatment of fungal infections of skin (HSDB 1990)Gavage
R: 0,3,15, M: 0,20,100 PPM/50 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE, CARCINOMA)
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA, CARCINOMA)
  • Lung: (ALVEOLAR/BRONCHIOLAR ADENOMA, ALVEOLAR/BRONCHIOLAR CARCINOMA)