National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/9812

Target Organs and Levels of Evidence for TR-226

Carcinogenesis Bioassay of C.I. Solvent Yellow 14 (CASRN 842-07-9) in F344/N Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
C.I. Solvent yellow 14
842-07-9
02/18/1981Monoazo dye in hydrocarbon solvents, oils, fats, shoe polish, gasoline, soapDosed-Feed
R: 0,250,500, M: 0,500,1000 PPM/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: NEOPLASTIC NODULE 5/50 10/50 30/50
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: NEOPLASTIC NODULE 2/50 3/49 10/48
Male Mice: Negative
Female Mice: Negative


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.