National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/7592

Target Organs and Levels of Evidence for TR-255

Toxicology and Carcinogenesis Studies of 1,2-Dichlorobenzene (o-Dichlorobenzene) (CASRN 95-50-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
1,2-Dichlorobenzene (o-dichlorobenzene)
95-50-1
09/22/1982Fumigant. Insecticide. Industrial solvent. Chemical intermediate. Degreasing agent for metals. Heat transfer medium. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Gavage
0,60,120 MG/KG/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative


NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.