National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13752

Target Organs and Levels of Evidence for TR-338

Toxicology and Carcinogenesis Studies of Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Erythromycin stearate
643-22-1
07/14/1987Antibacterial agent. Dosed-Feed
R: 0,5000,10000 M: 0,2500,5000 PPM/50 PER GROUP
Physiological Research Laboratory

Levels of Evidence

Male Rats: No Evidence
TypeOrgan/Tissue (Lesion)
Non-Neoplastic Lesions
  • LIVER: GRANULOMA 1/50 2/50 10/50
Female Rats: No Evidence
TypeOrgan/Tissue (Lesion)
Non-Neoplastic Lesions
  • LIVER: GRANULOMA 18/50 27/50 43/50
Male Mice: No Evidence
Female Mice: No Evidence


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