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Target Organs and Levels of Evidence for TR-373

Toxicology and Carcinogenesis Studies of Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Succinic anhydride
06/27/1989Food industry as dehydrator and acidulant. Chemical intermediate for adhesives, dyes, elastomers for special tubing, covering and extruded articles. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Gavage
R:0,50,100 MM: 0,38,75, FM: 0, 75, 150 MG/KG/60 PER GROUP
BioReliance, Inc

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence