Through HTS, the collaboration is testing a collection of more than 10,000 environmental chemicals, drugs, and formulations to broadly characterize and define their chemical reactivity in biochemical- and cell-based assays. Building on the strengths of each partner, Tox21 facilitates the advancement of toxicology to a more predictive science, based on the most relevant and meaningful tools of modern molecular biology and chemistry. The convergence of science, technology, regulatory need, and public opinion has created the opportunity to transform toxicology and risk assessment into more accurate, rapid, and cost-effective sciences. Additionally, Tox21 supports the goals of reduction, refinement, and replacement of animals in toxicity testing (NTP Interagency Center for the Evaluation of Alternative Toxicological Methods Tox21 activities).
For further information on NTP's Tox21 program, contact:
Richard S. Paules, Ph.D.
Acting Chief, Biomolecular Screening Branch
NIEHS/Division of NTP
P.O. Box 12233,
Research Triangle Park, NC 27709