On June 15, 2026, the National Institutes of Health (NIH) announced that moving forward, NICEATM will continue its important work as a division of the newly created NIH Office of Research Innovation, Validation, and Application (ORIVA). Soon, NICEATM content that you see on this webpage will be transitioned to the NIH ORIVA webpage. In the meantime, you can learn more about the new office and how it is structured.

https://ntp.niehs.nih.gov/go/commprac-2026

ICCVAM Communities of Practice Webinar 2026

Integration of NAMs Data into Regulatory Decision-making 

October 7, 2026

Slides and video from the webinar will be placed on this page when they have been formatted to meet government accessibility requirements. An announcement will be sent out via NICEATM News when they are posted.

ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods.  To support these goals, ICCVAM presents Communities of Practice webinars to provide detailed information on a current topic relevant to alternative test method development.

This webinar, organized on behalf of ICCVAM by NICEATM, considered the integration of new approach methodologies (NAMs) into regulatory decision-making. This follows the release by several U.S. and international regulatory agencies of stepwise roadmaps to improve the human relevance of safety assessments by promoting the adoption of scientifically qualified or validated NAMs, including human-based in vitro systems, in silico modeling, and other emerging technologies. Webinar speakers discussed how NAMs data can be incorporated into regulatory decision-making through defined approaches, weight-of-evidence frameworks, and integrated approaches to testing and assessment:

  • Iris Mangas from the European Food Safety Authority
  • Thomas Jackson, Rachel Brunner, and Anthony Luz from the U.S. Environmental Protection Agency
  • Nakissa Sadrieh from the U.S. Food and Drug Administration