Webinar Series

Current Concepts in Quantitative Risk Assessment for Skin Sensitization

Videos for all webinars are available below.

Allergic contact dermatitis is one of the most frequent occupational diseases associated with chemical exposure. Chemicals and pesticides must be tested for their potential to cause skin sensitization and there have been major developments in testing strategies in recent years, as new approach methods are becoming accepted alternatives to traditional animal tests. Despite this progress, quantitative risk assessment of skin sensitizing chemicals remains a challenging process.

This webinar series provided an overview of the current state of the science in this rapidly developing field. The webinars were intended as background for a planned workshop in 2022 on quantitative risk assessment of skin sensitizing pesticides but they are of interest to the broader scientific community as they are relying on the development of concepts and methods in other areas e.g. cosmetics, fragrances and consumer products.

The webinar series was organized by NICEATM, the Swiss Centre for Applied Human Toxicology, and the Swiss State Secretariat for Economic Affairs.

Webinar Schedule

Webinar 1, September 21, 2021: Introduction to skin sensitization and contact dermatitis.

Presentations:

• Skin sensitization: history and current state of play
  David Basketter, DABMEB Consultancy Ltd.
• Epidemiology of contact dermatitis with a focus on occupational exposure and monitoring of skin sensitizers
  Wolfgang Uter, University of Erlangen-Nurnberg

Webinar 2, December 8, 2021: Methods for hazard and exposure assessment.

Presentations:

• International progress in skin sensitization hazard and risk assessment
  Nicole Kleinstreuer, National Institute of Environmental Health Sciences
• Introduction to exposure and quantitative risk assessment of skin sensitising chemicals
  Denise Bloch, Federal Institute for Risk Assessment (Germany)

Webinar 3, March 9, 2022: Opportunities and new approaches for quantitative risk assessment.

Presentations:

• Next-generation quantitative risk assessment for skin sensitizing cosmetics and fragrances
  Petra Kern, Procter & Gamble
• Assessing skin sensitization potential and potency of pesticidal products with advanced NAMs
  Marco Corvaro, Corteva Agriscience, and Susanne Kolle, BASF