ICCVAM Communities of Practice Webinar 2025

Evolution of Complex In Vitro Models 

Monday July 21, 2025

Slides and video from the webinar will be available on the page when they are formatted to conform to U.S. government accessibility requirements. An announcement will be sent via NICEATM News when they are posted.

ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. This webinar, organized on behalf of ICCVAM by NICEATM, discussed current activities in development and validation of complex in vitro models. Scheduled speakers and topics included:

• Danilo Tagle, PhD, National Center for Advancing Translational Sciences (NCATS), will discuss NCATS' program on microphysiological systems (MPS), or "tissue chips." NCATS is the newest ICCVAM member agency.
• Ivan Rusyn, MD, PhD, Texas A&M University, will present an overview of the TEX-VAL Consortium for validation and qualification of MPS.
• Remi Villenave, PhD, Roche, will provide an industry perspective on adoption and validation of advanced models, including consideration of regulatory acceptance.

The webinar was open to the public with time scheduled for questions by participants following each presentation.