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https://ntp.niehs.nih.gov/go/natl-strategy

Strategic Roadmap: New Approaches to Evaluate the Safety of Chemicals and Medical Products

ICCVAM is coordinating the development of a strategic roadmap for incorporating new approaches into safety testing of chemicals and medical products in the United States. Scientific and technological advances in toxicology can significantly improve and protect public health. However, a national strategy is required to ensure the safe, effective, and timely implementation of human-based, predictive approaches in toxicity testing.

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The U.S. Strategic Roadmap: New Approaches to Evaluate the Safety of Chemicals and Medical Products (August 30 draft)

The primary objective of this strategy is to expedite the development and utilization of new approach methodologies that provide information more relevant to human health than existing animal-based methods. It is anticipated that focusing on human relevance will obviate the need for testing in animals, while also reducing the cost of product development and registration. A strategic roadmap will help establish the use of these new approaches by providing a conceptual framework to support the development, evaluation, and utilization of new approach methodologies and facilitate communication and collaboration within and between government agencies, stakeholders, and international partners.