Presentations at 11th World Congress on Alternatives and Animal Use
August 23-September 2, 2021
Oral Presentations
S111: Modern, Mechanistic Approaches to Cancer Risk Assessment
Abstract Number 11: Modernizing the NTP's Carcinogenicity Testing Program
Speaker: W Casey (ICCVAM member, NIEHS)
S126: Modern Regulatory Methods for Skin Sensitization: Bye-Bye Buehler?
Abstract Number 48: A North American Regulatory Perspective on Skin Sensitization Risk Assessment
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
S205: A Virtual Human Platform for Safety Assessment
Abstract Number 1000: Comparing and Interpreting Tox21 Data Analysis Approaches
Speaker: A Karmaus (ILS, contractor supporting NICEATM)
S160: Human Organs-on-Chips: Advancing Regulatory Science Through Innovation
Suzanne Fitzpatrick (ICCVAM member, FDA) was session chair.
Abstract Number 946: Developing Performance Based Qualification Criteria for Organs on a Chip
Speaker: S Fitzpatrick (ICCVAM member, FDA)
S60: New Approach Methods in AgroChemical Development and Regulatory Decisions
Abstract Number 68: Waiving Repeat Dose Studies While Confidently Protecting Human Health from Exposure to Agricultural Chemicals
Speaker: M Perron (ICCVAM workgroup member, EPA)
S181: Use of New Approach Methodologies - NAMs - to Derive Point(s) of Departure; Opportunities and Limitations
Abstract Number 49: Applying In Vitro to In Vivo Extrapolation to NAM-derived PODs
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
S315: EPAA Training Session on Skin Sensitisation
Keynote Introduction to Skin Sensitisation NAMs and Defined Approaches
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
S59: Innovative Technologies Integrating Standardised Regulatory Test Methods: Challenges and Perspectives
Abstract Number 297: Integrating Innovative Methods to Predict a Regulatory Hazard Endpoint: a Regulatory Perspective
Speaker: M Perron (ICCVAM workgroup member, EPA)
S104: AOPs, MOAs, and KCs - Mutually Informative, Not Mutually Exclusive
Abstract Number 47: Building an AOP-Driven Defined Approach Guideline
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
S26: "Proof in Animals": Has Journal Editorial Policy Fallen Behind Advances in Human-based Approaches
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
S313: Roadmap
Abstract Number 1008: Improving Alternative Method Adoption Through Tools and Resources to Support Community Knowledge
Speaker: S Bell (ILS, contractor supporting NICEATM)
S312: QIVIVE
N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS) was session chair.
Abstract Number 442: In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Valproic Acid Analogues
Speaker: X Chang (ILS, contractor supporting NICEATM)
Poster Presentations
Abstract P225: Retrospective Analysis of Dermal Triple Pack Data
Presenter: DG Allen (ILS, contractor supporting NICEATM)
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Abstract P230: Mixture-based QSAR Models of Ocular Toxicity for Regulatory Hazard Categories
Presenter: A Sedykh (Sciome, contractor supporting NICEATM)
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Abstract P232: Rat Acute Systemic Toxicity Testing: Evaluating Reproducibility and Inherent Variability
Presenter: A Karmaus (ILS, contractor supporting NICEATM)
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Abstract P268: Retrospective Evaluation of the Acute Fish Toxicity Test for Pesticide Registration
Presenter: P Ceger (ILS, contractor supporting NICEATM)
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Abstract P505: Developing a Defined Approach for Eye Irritation Testing
Presenter: N Choksi (ILS, contractor supporting NICEATM)
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Abstract P508: OPERA, an Open-source and Open-data Suite of QSAR Models
Presenter: K Mansouri (NIEHS/NICEATM)
Abstract P509: Variability in the Rabbit Skin Irritation Assay
Presenter: JP Rooney (ILS, contractor supporting NICEATM)
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Abstract P511: Application of Defined Approaches for Skin Sensitization to Agrochemical Products
Presenter: J Strickland (ILS, contractor supporting NICEATM)
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Abstract P513: Effective User Support Documentation for a Toxicological Data Resource: ICE as a Case Study
Presenter: C Sprankle (ILS, contractor supporting NICEATM)
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Abstract P572: Performance of the GHS Mixtures Equations for Predicting Acute Oral Toxicity
Presenter: J Hamm (ILS, contractor supporting NICEATM)
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Abstract P576: Standardizing Developmental Toxicology Study Extractions Using Automated Application of Ontologies
Presenter: C Foster (ICF; collaboration with NICEATM)
Abstract P577: High-throughput Screening to Predict HERG Inhibition
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
Abstract P578: Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)
Abstract P586: International Regulatory Needs for Acute Toxicity Data
Presenter: J Strickland (ILS, contractor supporting NICEATM)
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