NICEATM Abstracts Published Since 2021
| Year Presented | Authors | Title | Presentation Venue |
|---|---|---|---|
| 2025 | Chen Y, Salazar K, Mansouri K, Kleinstreuer N | A machine learning approach for predicting inhalation acute toxicity (LC50) values of chemicals using a two-stage regression model | Society of Toxicology |
| 2025 | Krishna S, Chang X, Eccles K, Messier K, Kleinstreuer N | Multiscale risk characterization of chemical cardiotoxicity: integrated in vitro and in silico multiscale modeling reveals cardiovascular risk from chemical exposures | Society of Toxicology |
| 2025 | Tropsha A, Muratov E, Kleinstreuer N | Systemic and topical toxicity (STOPTOX) predictor: model development and external validation | Society of Toxicology |
| 2025 | Kleinstreuer N | Advancing one health preparedness: integrating computational dynamic and kinetic systems models into regulatory frameworks | Society of Toxicology |
| 2025 | Yang S, Knudsen T, Carstens K, Hogberg HT, Xia M | Development of a high-throughput assay platform for neuroinflammation detection using iPSC-derived microglia | Society of Toxicology |
| 2025 | Kleinstreuer N | Building and applying high-confidence computational models in med tech | Society of Toxicology |
| 2025 | Haber L, Bradley MA, Martin EM, Snow SJ, Robertson JM, Fies W, Borrel A, Reinke E, Bevington C, Gordon J, Cho T, Hooker E, Hatlelid K | Class-based hazard and dose-response assessment of polyhalogenated organophosphate flame retardants | Society of Toxicology |
| 2025 | Scheufen Tieghi R, Moreira-Filho J, Martin H, Wellnitz J, Otoch MC, Rath M, Tropsha A, Muratov E, Kleinstreuer N | Using ML for human skin sensitization prediction - a novel in silico tool using HPPT data | Society of Toxicology |
| 2025 | Moreira-Filho J, Ranganath D, Tieghi R, Patton R, Sutherland V, Schmitt C, Rooney A, Walker V, Fostel J, Saddler T, Reif D, Mansouri K, Kleinstreuer N | Automating data extraction from scientific literature and general PDF files using large language models and KNIME: An application in toxicology | Society of Toxicology |
| 2025 | Hogberg H | Integrated approaches to testing and assessment case study of mifepristone to determine developmental neurotoxic potential | Society of Toxicology |
| 2025 | Ehrlich D, Krishna S, Kleinstreuer N | Data-driven derivation of an adverse outcome pathway linking vascular endothelial growth factor receptor (VEGFR), endocrine disruption, and atherosclerosis | Society of Toxicology |
| 2025 | Modaresi S, Salminen AT, Davis KJ, Felton RP, Sun J, Beland FA, Derr K, Brown PC, Ferrer M, Katz LM, Kleinstreuer NC, Leshin J, Manga P, Sadrieh N, Xia M, Fitzpatrick SC, Camacho L | Evaluation and comparison of in vitro permeation testing (IVPT) and barrier function in alternative skin models and excised human skin | Society of Toxicology |
| 2025 | Kruetz A | In vitro to in vivo extrapolation application for assessing developmental neurotoxicity | Society of Toxicology |
| 2025 | Scheufen Tieghi R | DeTox: An in silico alternative to animal testing for predicting developmental toxicity potential | Society of Toxicology |
| 2025 | Sakamuru S, Sukhawanit R, Wood S, Huang R, Klumpp-Thomas C, Simeonov A, Kleinstreuer N, Knudsen TB, Xia M | Inhibitors of Cytochrome P450 26A1 identified from screening the Tox21 10K compound library | Society of Toxicology |
| 2025 | Ranganath D, Moreira-Filho JT, Collins BJ, Waidyanatha S, Casey W, Kleinstreuer N, Mansouri K | Democratizing cheminformatics: case studies using the MoVIZ pipeline for automated chemical grouping and toxicological insights | Society of Toxicology |
| 2025 | Unnikrishnan A, To KT, Herzler M, Germolec D, Reinke E, Kleinstreuer N | Web Application to Classify and Subcategorize Skin Sensitizers Using Human Data | Society of Toxicology |
| 2025 | Kreutz A, Karmaus AL, Oyetade OB, Paul Friedman K, Allen DG, Reinke EN, Paparella M, Kleinstreuer NC | Quantifying the Reproducibility and Variability of In Vivo Guideline Toxicology Studies | Society of Toxicology |
| 2025 | Hill B, Hamm J, Hsieh JH, Reinke EN, Hogberg HT, Ryan K | Understanding the Range of Phenotypic Responses for the Embryonic Zebrafish Developmental Toxicity Assay | Society of Toxicology |
| 2025 | Cuomo D, Karmaus A, Hill B, Feshuk M, Osborne G, Blake B, Druwe I, Wang A, Rigutto G, McHale C, Smith MT, Facchin C, De Conti A, Madia F, Kleinstreuer N, Chiu WA, Borrel A | Mapping ToxCast/Tox21 High-throughput Screening Assay Endpoints to Key Characteristics of Carcinogens | Society of Toxicology |
| 2024 | Daniel A, van der Zalm A, Raabe H, Clippinger A, Reinke E, Allen D, Kleinstreuer N | Defined Approaches for Predicting GHS and EPA Eye Irritation Classification of Agrochemicals | American Society for Cellular and Computational Toxicology |
| 2024 | Reinke E, Ulrey A, Hoffman S, Basketter D, Corsini E, Ashikaga T, Gerberick GF | Peer Review for Validation Studies - Building Confidence and Transparency into a New Validation Paradigm | American Society for Cellular and Computational Toxicology |
| 2024 | Borrel A, Cuomo D, Hill B, Reisfeld B, Karmaus A, Osborne G, Feshuk M, Blake B, Druwe I, Wang A, Bisson W, Madia F, Facchin C, De Conti A, Rigutto G, McHale C, Smith M, Chiu WA, Kleinstreuer N | Mapping Tox21/ToxCast HTS Data to Key Characteristics of Carcinogens | American Society for Cellular and Computational Toxicology |
| 2024 | Fies W, Luh J, Snow S, Martin E, Haber L, Bradley M, Reinke E, Borrel A, Hooker E, Bevington C, Gordon J, Cho T | Class-based Hazard, Exposure, and Dose-response Assessment of Polyhalogenated Organophosphate Flame Retardants | American Society for Cellular and Computational Toxicology |
| 2024 | Oyetade O, Kreutz A, Chang X, Hsieh JH, Behl M, Reinke E, Hogberg H | Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) to Prioritize Aromatic Organophosphorus Flame Retardants | American Society for Cellular and Computational Toxicology |
| 2024 | To KT, Borrel A, Reinke E, Kleinstreuer N | DASS App v2.0: Implementing OECD Guideline No. 497 Updates | American Society for Cellular and Computational Toxicology |
| 2024 | Reinke E, Gilmour N, Reynolds G, Reynolds J, Marco B, Borrel A, Maxwell G, Kleinstreuer N | SARA-ICE: A Self-contained Model for Predicting a Human-relevant Point-of-departure for Skin Sensitization | American Society for Cellular and Computational Toxicology |
| 2024 | Scheufen Tieghi R, Moreira-Filho JT, Martin HJ, Wellnitz J, Otoch C, Rath M, Tropsha A, Muratov EN, Kleinstreuer N | HuSSPred: an in-silico HPPT-based tool for Human Skin Sensitization Prediction | American Society for Cellular and Computational Toxicology |
| 2024 | Scheufen Tieghi R, Moreira-Filho JT, Rath M, Wellnitz J, Martin HJ, Gates K, Hogberg-Durdock HT, Kleinstreuer N, Tropsha A, Muratov EN | DeTox: An In Silico Alternative to Animal Testing for Predicting Developmental Toxicity Potential | American Society for Cellular and Computational Toxicology |
| 2024 | LaPratt T, Hull V, Reinke E, Kleinstreuer N | Structure-based Chemical Taxonomy to Focus Chemical Queries | American Society for Cellular and Computational Toxicology |
| 2024 | Reisfeld B, Borrel A, Chang X, Daniel A, Hill B, Hull V, To KT, Unnikrishnan A, Green A, McAfee E, Phillips J, Reinke E, Mansouri K, Kleinstreuer N | The Integrated Chemical Environment (ICE): Advancing Data Availability and Computational Tool Accessibility for the Development, Evaluation, and Application of New Approach Methods | American Society for Cellular and Computational Toxicology |
| 2024 | Unnikrishnan A, To KT, Borrel A, Hull V, Daniel A, Reinke E, Kleinstreuer N | Harmonizing Tox Data to Enhance Confidence and Utility | American Society for Cellular and Computational Toxicology |
| 2024 | Hill B, Auman JT, Unnikrishnan A, Karmaus A, Hogberg H, Reinke E, Kleinstreuer N | Incorporating Ontologies into High-Throughput Screening Assay Annotations to Facilitate Interpretation and Increase Data Use | American Society for Cellular and Computational Toxicology |
| 2024 | Germolec D | GARDAir Testing of Federal Agency Partners Chemicals of Concern | American Society for Cellular and Computational Toxicology |
| 2024 | Kleinstreuer N | Cardiotoxicity NAMs Across the Translational Toxicology Pipeline | American Society for Cellular and Computational Toxicology |
| 2024 | Chang X | In Vitro to In Vivo Extrapolation Application to Promote the Use of NAMs for Assessing Inhalation Toxicity | Society of Toxicology |
| 2024 | Lane TR, Snyder S, Harris JS, Hamm J, Urbina F, Unnikrishnan A, Borrel A, Karmaus A , Behl M, Hogberg-Durdock H | Seizure Predictions Using Adverse Outcome Pathway-Based Fast Interpretable Greedy-Tree Sums Modeling | Society of Toxicology |
| 2024 | Krishna S, Beverly B, Walker VR, Kleinstreuer NC, Hannani A, Whately H, Trgovcich J, Rochester J, Sprowles J, Miller M, Tracy W, Sibrizzi C, Rooney AA | Artificial Intelligence Approaches to Identify and Categorize Health-Relevant Research for Big Questions: Case Study of Cardiovascular Disease and Environmental Exposures | Society of Toxicology |
| 2024 | Whitehead TM, Strickland J, Conduit GJ, Borrel A, Mucs D, Baskerville-Abraham I | Toxicological Data Gap Filling of Ingredients; Comparison of Machine Learning Based Imputation and Traditional QSAR Methods | Society of Toxicology |
| 2024 | Moreira-Filho J, Ranganath D, Conway M, Waidyanatha S, Collins B, Schmitt C, Kleinstreuer N, Mansouri K | Modeling and Visualization (MoVIZ): Democratizing Cheminformatics with a User-friendly Guided Pipeline | Society of Toxicology |
| 2024 | Hsieh J, Wang Z, Nolte S, Marvel S, Hill B, Hamm J, Roberts G, Schmitt, Ryan K | SEAZIT-DIVER: A Web Application for Integrating and Visualizing Inter-laboratory Data on Substance-Induced Developmental Toxicity Phenotypes in Zebrafish Embryos | Society of Toxicology |
| 2024 | McPherson CA, Combs P, Cushman J, Erickson J, Hsieh J, Hall L, Hogberg HT, Kendricks K, Sills R | Integrating Screening Level Developmental Neurotoxicity (DNT) Information of Chemicals in a New Approach Methods (NAMs) Battery to Identify Compounds for Future Study | Society of Toxicology |
| 2024 | Sutherland V, Hogberg HT, Behl M, Hsieh J, Mansouri K, Mehta S, Roberts G, Ryan K, Taylor KW, Walker N, Walker VR, Witchey S, Rooney AA | Organophosphate Flame Retardants: A Comprehensive Toxicological Assessment | Society of Toxicology |
| 2024 | Scheufen Tieghi R, Rath MK, Moreira-Filho JT, Martin H, Beasley J, Hogberg HT, Kleinstreuer N, Muratov E | PregPred: A Model to Predict the Developmental Toxicity Potential of Environmental Chemicals and FDA-Approved Drugs and Cosmetics | Society of Toxicology |
| 2024 | Borrel A | Deep-Learning Profile QSAR Modeling to Impute In Vitro Assay Results and Predict Chemical Carcinogenesis Mechanisms | Society of Toxicology |
| 2024 | de Aguiar Marciano L, Filipe Costa L, Silva Cardoso N, de Araújo Paula F, Pupin Silvério A, Kleinstreuer N, Martins I | Risk Assessment of Exposure to Triazole Fungicides by Human Biomonitoring and Mechanistic Data | Society of Toxicology |
| 2024 | Hogberg-Durdock H, Hamm J, Borrel A, Karmaus A , Lane T, Unnikrishnan A, Urbina F, Behl M | Identifying Seizure-Inducing Biological Targets: A Collaborative Approach Using AOP Networks, In Vitro Assays, and Computational Tools | Society of Toxicology |
| 2024 | Unnikrishnan A, Chang X, Kreutz A, Hull V, Tedla GE, Hogberg HT, Sluka JP, Wambaugh JF, Allen DG, Kleinstreuer N | PBPK Modeling to Predict Chemical Distribution in Brain and Adipose Tissues | Society of Toxicology |
| 2024 | Tedla G, Borrel A, Karmaus A, Hull V, To KT, Auman JT, Allen DG, Kleinstreuer N | Machine learning-based development of cytotoxicity flags within the Tox21/ToxCast assays | Society of Toxicology |
| 2024 | Sullivan K, Reinke E, Macmillan DS, Raabe H, Germolec D, Allen D, Choi E, Filipovska J, Kleinstreuer N | Advancing Flexibility for Defined Approach Guidelines: Developing Performance Standards to Incorporate Alternate Information Sources into the Defined Approach for Skin Sensitization Guideline | Society of Toxicology |
| 2024 | Reinke EN, LaPratt T, Strickland JA, Germolec D, Truax J, Reynolds J, Reynolds G, Gilmour N, Allen DG, Maxwell G, Kleinstreuer NC | Application of the SARA-ICE Skin Sensitization Defined Approach to a Diverse Chemical Set – a Comparative Case Study | Society of Toxicology |
| 2024 | Oyetade OB, Chang X, Kreutz A, Hsieh JH, Behl M, Sipes N, Allen DG, Hogberg HT | OPFR Prioritization using the Developmental Neurotoxicity In Vitro Test Battery: An Update to OECD IATA Case Study | Society of Toxicology |
| 2024 | Maxwell G, Reynolds J, Gilmour N, Strickland J, Reinke EN, Germolec D, Truax J, Allen DG, Blaylock M, LaPratt T, Reynolds G, Kleinstreuer N | Application of Skin Allergy Risk Assessment-Integrated Chemical Environment Defined Approach (SARA-ICE DA) to Assess Skin Sensitization Potency of Isothiazolinone Compounds | Society of Toxicology |
| 2024 | Kreutz A, Chang X, Lawless M, Shafer TJ, Wambaugh JF, Wetmore BA, Allen DG, Hogberg HT | In Vitro to In Vivo Extrapolation for Developmental Neurotoxicity: A Comparison of Physiologically Based Pharmacokinetic Models | Society of Toxicology |
| 2024 | Johnson VJ, Reinke EN, LaPratt TR, Strickland J, To KT, Larne O, Johansson H, Forreryd A, Allen DG, Kleinstreuer NC, Germolec DR | Testing of Regulatory-Relevant Chemicals for Skin and Respiratory Sensitization Hazard | Society of Toxicology |
| 2024 | Hull V, LaPratt TR, Karmaus AL, To KT, Unnikrishnan A, Allen DG, Kleinstreuer NC | Curating chemical use categories and exposure predictions to inform chemical assessment | Society of Toxicology |
| 2024 | Hill BN, Reinke EN, Auman JT, Unnikrishnan A, Allen DG, Kleinstreuer NC | Incorporating Ontologies into High Throughput Screening Assay Annotations to Increase Data Use and Interpretation | Society of Toxicology |
| 2024 | Daniel AB, van der Zalm AJ, Raabe HA, Clippinger AJ, Kleinstreuer NC, Allen DG | Predicting GHS Hazard Classification for Eye Irritation/Corrosion Potential of Agrochemical Formulations Using Defined Approaches | Society of Toxicology |
| 2024 | Chang X, Palmer J, Donley E, Reinke E, Allen D, Kleinstreuer N | IVIVE to Facilitate Animal-free Risk Assessment of Potential Developmental Toxicants | Society of Toxicology |
| 2024 | Borrel A, Tedla G, To KT, Hill B, Karmaus AL, Wang A, Luechtefeld T, Reif D, Allen DG, Kleinstreuer NC | Modern In Vitro Imputation Modeling and Machine Learning to Predict Chemical Carcinogenicity | Society of Toxicology |
| 2024 | Allen DG, Hull V, Reinke EN, Daniel AB, To KT, Karmaus AL, Mansouri K, Kleinstreuer NC | Curation and Characterization of a Reference Rat Acute Inhalation Toxicity Database | Society of Toxicology |
| 2024 | Marko S, Allen DG, Hogberg H, Oyetade OB, Kleinstreuer NC, Carder J | Opportunities for Encouraging the Consideration of Alternative Methods | Society of Toxicology |
| 2023 | Borrel A, Unnikrishnan A, Allen D, Kleinstreuer N | ChemMaps.com v2.0 - Exploring the Environmental Chemical Universe | Southeast Regional Meeting of the American Chemical Society |
| 2023 | Borrel A, Unnikrishnan A, Allen D, Kleinstreuer N | ChemMaps.com v2.0 - Exploring the Environmental Chemical Universe | American Society for Cellular and Computational Toxicology |
| 2023 | Borrel A, Karmaus AL, Tedla G, Mansouri K, Luechtefeld T, Lunn R, Wang A, Allen D, Kleinstreuer N | Deep Learning Profile QSAR Modeling to Impute In Vitro Assay Results and Predict Chemical Carcinogenesis Mechanisms | American Society for Cellular and Computational Toxicology |
| 2023 | Hull V, Reinke EN, Daniel AB, To KT, Karmaus AL, Allen DG, Mansouri K, Kleinstreuer NC | Compilation and Standardization of Rat Acute Inhalation Study Data to Support Predictive Modeling | American Society for Cellular and Computational Toxicology |
| 2023 | Hull V, LaPratt T, Karmaus AL, To KT, Unnikrishnan A, Allen DG, Kleinstreuer NC | Curating Chemical Use Categories and Exposure Predictions to Inform Chemical Assessment | American Society for Cellular and Computational Toxicology |
| 2023 | To KT, Strickland J, Reinke E, Borrel A, Truax J, Allen D, Kleinstreuer N | Web Application to Predict Skin Sensitization Using Defined Approaches | American Society for Cellular and Computational Toxicology |
| 2023 | Herzler M, To KT, Unnikrishnan A, Abedini J, Allen D, Germolec D, Gordon J, Kleinstreuer K, Ko HS, Matheson J, Thierse HJ, Truax J, Vanselow JT, Strickland J | Evaluation of Skin Sensitization Classification Rules to Reflect Induction Potency in Humans | American Society for Cellular and Computational Toxicology |
| 2023 | Unnikrishnan A, Chang X, Hull V, Tedla GE, Hogberg H, Sluka J, Wambaugh J, Allen D, Kleinstreuer N | Expanding PBPK Modeling to Predict Chemical Distribution in Brain and Adipose Tissues | American Society for Cellular and Computational Toxicology |
| 2023 | Unnikrishnan A, Hull V, Chang X, Borrel A, To K, Karmaus A, Phillips J, McAfee E, Allen D, Kleinstreuer N | Facilitating NAM-Based Chemical Assessments with the Integrated Chemical Environment | American Society for Cellular and Computational Toxicology |
| 2023 | Hogberg H, Behl M, Combs P, Cushman J, Erickson J, Hall L, Hsieh JH, Kendricks D, Kreutz A, Stanko J, Thomas D, Wilson L, Zhang X, Sills R, McPherson C | Generating Screening Level Developmental Neurotoxicity (DNT) Information of Chemicals in a New Approach Methods (NAMs) Battery | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Daniel A, van der Zalm A, Raabe H, Clippinger AJ, Kleinstreuer N, Allen D | Defined Approaches for GHS Categorization to Assess Eye Irritation Potential of Agrochemical Formulations | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Wittwehr C, Chang X, Bisson W, Culbreth M, Edwards SW, Ferguson S, Harrill A, Hogberg H, Karmaus AL, Leite SB, Lekka E, Kleinstreuer NC, Markey KJ, Masci AM, Mennecozzi M, Mortensen HM, O'Brien JM, Reinke E, Schmitt C, Tucker NN, Virvilis V | Methods2AOP: An International Collaboration Advancing AOP Key Event Descriptions | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Unnikrishnan A, Chang X, Karmaus AL, Hull V, Allen DG, Kleinstreuer NC | Expanding PBPK Modeling to Predict Chemical Distribution in Brain and Adipose Tissues | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Unnikrishnan A, Karmaus AL, Hull V, Chang X, Borrel A, To KT, Daniel A, Cooper S, Phillips J, McAfee E, Allen DG, Kleinstreuer NC | ICE Data and Tools to Advance NAMs | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | To KT, Oyetade O, Allen DG, Harrill A, Kleinstreuer N, Hogberg HT | Using NAMs to Address Variability and Susceptibility Across Populations | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | To KT, Strickland J, Borrel A, Truax J, Allen DG, Kleinstreuer N | Web Application to Predict Skin Sensitization Using Defined Approaches | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Strickland J, Truax J, To KT, Reinke EN, Gulledge T, Johnson VJ, Allen DG, Kleinstreuer NC, Germolec D | Defined Approaches for Skin Sensitization for Diverse Chemical Sets | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Reinke EN, Daniel AB, Hull VH, To KT, Karmaus AL, Allen DG, Mansouri K, Kleinstreuer NC | Development and Curation of an Acute Inhalation Toxicity Database | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Reinke EN, Strickland J, Truax J, To KT, Gulledge T, Johnson VJ, Larne O, Johansson H, Forreryd A, Allen DG, Kleinstreuer NC, Germolec D | Evaluating Skin Sensitization Hazard of Diverse Chemicals Using GARDskin | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Oyetade OB, Karmaus AL, Reinke E, Allen DG, Kleinstreuer N | Variability of In Vivo Toxicology Studies: Impact on NAMs | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Maxwell G, Reynolds G, Reynolds J, Gilmour N, Strickland J, Reinke EN, Germolec D, Truax J, Allen DG, Kleinstreuer N | The SARA-ICE Model for Predicting Skin Sensitizer Potency | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Lee S, Borrel A, To KT, Li T, Liu Z, Tong W, Benfenati E, Roncaglioni A, Manganaro A, Mansouri K, Kleinstreuer NC | Applying In Silico Toxicity Models Across the Tox21 Chemical Universe | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Karmaus AL, Borrel A, Unnikrishnan A, Wittwehr C, Kleinstreuer NC | Annotating High-Throughput Screening Assays: Facilitating Interpretation and Data Use | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Karmaus AL, Medvedev A, Hull V, Reinke EN, Daniel AB, Allen DG, Kleinstreuer N, Casey W | Insights from Profiling Transcription Factor Transactivation with CYP450 Metabolism Integration | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Hull V, Hines D, Unnikrishnan A, Karmaus AL, Allen DG, Dorne JLCM, Erickson J, Combs P, Ferguson S, Mansouri K, Kleinstreuer N | Integrating Enzyme Variability Into PB-K Models of Chemicals and Metabolites | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Hull V, Karmaus AL, To KT, Unnikrishnan A, Allen DG, Kleinstreuer N | Curating Chemical Use and Exposure Predictions to Contextualize Chemical Hazard | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Hull V, Borrel A, Karmaus AL, Allen DG, Kleinstreuer N | Integration of Technological Interference into Curated HTS Data | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Herzler M, Abedini J, To KT, Allen DG, Api AM, Germolec D, Gordon J, Kleinstreuer N, Ko H-S, Matheson J, Thierse H-J, Truax J, Vanselow JT, Strickland J | Evaluation of Skin Sensitization Classification Rules to Reflect Human Potency | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Gordon J, Truax J, Borrel A, Reinke EN, Adams V, Rua D, Petersen E, Uhl R, Elliott J, Gutierrez R, Johnson VJ, Germolec D, Allen DG, Kleinstreuer NC, Strickland J | Validation of the Electrophilic Allergen Screening Assay (EASA) | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Daniel A, Kleinstreuer N, Allen D, Blaylock M, Glover K, Goralski T, Kerr C, Tagle D, Williams M, Holmes A | A Working Group Supporting Adoption of MPS in Infectious Disease Research | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Chang X, Reinke E, Daniel A, Allen DG, Kleinstreuer N, Mumtaz MM | Using In Vitro Data and PBPK Models to Predict Inhalation Toxicity | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Carder J, Allen DG, Hogberg H, Oyetade O, Kleinstreuer N, Marko S | Opportunities for Encouraging the Consideration of Alternative Methods | 12th World Congress on Alternatives and Animal Use in the Life Sciencess |
| 2023 | Borrel A, Karmaus AL, Tedla G, Mansouri K, Luechtefeld T, Lunn R, Wang A, Allen DG, Kleinstreuer N | Deep Learning Profile QSAR Modeling to Impute In Vitro Assay Results and Predict Chemical Carcinogenesis Mechanisms | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Borrel A, Unnikrishnan A, Allen DG, Kleinstreuer N | ChemMaps.com V2 - Exploring the Environmental Chemical Universe | 12th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2023 | Kleinstreuer NC | Establishing Confidence in NAMs for Developmental and Reproductive Toxicology | Society for Birth Defects Research and Prevention |
| 2023 | Kleinstreuer NC | AI-Assisted Insights into Developmental Disruption | Society for Birth Defects Research and Prevention |
| 2023 | Beardslee RA, Salazar K, van der Zalm A, Camacho IA, Brunner R, Raabe H, Allen D, Daniel A, Kleinstreuer N, O’Dell L, Clippinger A, Scarano L, Lowit A | Evaluating New Chemicals in the U.S. under the Toxic Substances Control Act (TSCA): Application of New Approach Methods (NAMs) to Evaluate Eye Irritation | Society of Toxicology |
| 2023 | Borrel A, Unnikrishnan A, Fourches D, Allen DG, Kleinstreuer N | ChemMaps.com V2 – Exploring the Environmental Chemical Universe | Society of Toxicology |
| 2023 | Karmaus AL, Borrel A, Feshuk M, Harrill A, Wittwehr C, Kleinstreuer NC | Annotations for ToxCast and Tox21 High-Throughput Screening Assays: Facilitating Assay Interpretation and Data Use | Society of Toxicology |
| 2023 | Wittwehr C, Chang X, Bisson W, Edwards SW, Ferguson S, Harrill A, Hogberg H, Karmaus AL, Leite SB, Lekka E, Kleinstreuer NC, Markey KJ, Masci AM, Mennecozzi M, Mortensen HM, O’Brien JM, Reinke E, Schmitt C, Tucker NN, Virvilis V | Methods2AOP: An International Collaboration to Integrate Assay Annotations into the AOP Key Event Descriptions | Society of Toxicology |
| 2023 | Unnikrishnan A, Karmaus AL, Hull V, Chang X, Borrel A, To KT, Daniel A, Cooper S, Phillips J, McAfee E, Allen DG, Casey W, Kleinstreuer N | Integrated Chemical Environment: An Advanced Platform Aiding NAM-based Chemical Assessments | Society of Toxicology |
| 2023 | To KT, Strickland J, Borrel A, Truax J, Allen DG, Kleinstreuer NC | DASS App: A Web Application for Applying Defined Approaches for Skin Sensitization to Predict Hazard and Potency Categorization | Society of Toxicology |
| 2023 | Sakamuru S, Ma D, Pierro JD, Baker NC, Kleinstreuer N, Cali JJ, Knudsen TB, Xia M | Development and Validation of Enzyme-Based CYP26A1 Inhibition Assay in a High-Throughput Screening Platform | Society of Toxicology |
| 2023 | Ramaiahgari S, Krishna S, Kleinstreuer N, Liu J, Auerbach SS, Beverly B, Merrick BA, Berridge BR | In Vitro Assessment of Environmental Chemical Hazards on Cardiovascular Diseases | Society of Toxicology |
| 2023 | Rooney AA, Mansouri K, Bevington C, Hatlelid K, Helmick K, Blain R, Hannani A, Tracy W, Peppriell A, Cooney G, Sibrizzi C, Taylor K, Shipkowski K, Walker V | An Informatics Approach to Inform a Class-Based Analysis of Health Effects Associated with Exposure to Organohalogen Flame Retardants | Society of Toxicology |
| 2023 | Herzler M, Abedini J, To KT, Allen DG, Api AM, Germolec D, Gordon J, Kleinstreuer NC, Ko H, Matheson J, Thierse H, Truax J, Vanselow J, Strickland J | Evaluation of Skin Sensitization Classification Rules to Reflect Human Potency | Society of Toxicology |
| 2023 | Kleinstreuer N | Computational Crowdsourcing to Understand and Address Regulatory Needs: Case Studies for Prioritization of Environmental Chemicals Using AI/ML Approach | Society of Toxicology |
| 2023 | Mansouri K | Applications of Class-Based Approaches in Risk Assessment and Toxicological Research | Society of Toxicology |
| 2023 | Daniel AB, van der Zalm AJ, Clippinger AJ, Kleinstreuer NC, Allen DG | Three-Phase Testing of Agrochemical Formulations: Developing a Defined Approach for Eye Irritation Potential | Society of Toxicology |
| 2023 | Medvedev A, Karmaus AL, Hull V, Reinke EN, Daniel AB, Allen DG, Kleinstreuer NC, Casey W | Mechanistic Insights from Profiling Chemical-Mediated Transcription Factor Transactivation with the Integration of Cytochrome P450 Metabolism | Society of Toxicology |
| 2023 | Kleinstreuer N | Human Biological Relevance: Topical Toxicity Case Studies | Society of Toxicology |
| 2023 | Mansouri K, Martin T, Chang X, Williams A, Kleinstreuer N | OPERA Models Supporting Regulatory Needs | Society of Toxicology |
| 2023 | Moreira Filho J, Conway M, Schmitt C, Kleinstreuer N, Mansouri K | Interpretable Chemical Grouping Using an Automated KNIME Workflow | Society of Toxicology |
| 2023 | Chang X, Reinke EN, Daniel AB, Allen DG, Mumtaz MM, Kleinstreuer NC | Combining NAM Data and IVIVE for Evaluating Potential Inhalation Toxicity | Society of Toxicology |
| 2023 | Hull V, Hines D, Unnikrishnan A, Karmaus AL, Allen DG, Dorne JC, Erickson J, Combs P, Ferguson S, Kleinstreuer NC, Mansouri K | Integrating Population Enzyme Variability into Physiologically Based Kinetic Models of Parent Chemicals and Metabolites | Society of Toxicology |
| 2023 | Karmaus AL | Leveraging In Vivo Variability to Assess Performance of Predictive Models and the Role of Reanalysis to Build Confidence via Consensus | Society of Toxicology |
| 2023 | Gordon J, Truax J, Borrel A, Reinke EN, Adams V, Rua D, Petersen E, Uhl R, Allen DG, Kleinstreuer NC, Strickland J | Validation of the Electrophilic Allergen Screening Assay (EASA) to Detect Substances That Impact the Initial Key Event in the Adverse Outcome Pathway for Skin Sensitization | Society of Toxicology |
| 2023 | Strickland J, Truax J, To KT, Reinke EN, Gulledge T, Johnson VJ, Allen DG, Kleinstreuer NC, Germolec D | Application of Defined Approaches for Skin Sensitization for Chemicals of Federal Agency Interest | Society of Toxicology |
| 2023 | Reinke EN, Corsini E, Ono A, Fukuyama T, Ashikaga T, Gerberick GF | Peer Review Report of the EpiSensA Skin Sensitization Assay | Society of Toxicology |
| 2023 | Lee S, Borrel A, To KT, Li T, Liu Z, Tong W, Benfenati E, Roncaglioni A, Manganaro A, Mansouri K, Kleinstreuer NC | Applying In Silico Toxicity Models across the Tox21 Chemical Universe | Society of Toxicology |
| 2023 | Hogberg-Durdock H, Lam A, Elan O, Shahbaz MA, Clerbaux L, Bal-Price A, Coecke S, Concha R, De Bernardi F, Edrosa E, Hargreaves AJ, Kanninen KM, Munoz A, Pistollato F, Saravanan S, Garcia-Reyero N, Wittwehr C, Sachana M | The Adverse Outcome Pathway Framework Applied to Neurological Symptoms of COVID-19 | Society of Toxicology |
| 2023 | Eccles KM, Karmaus AL, Kleinstreuer NC, Parham F, Wambaugh JF, Messier KP | Mapping a Path to Disease: Quantifying the Risk of Exposure to Environmental Chemical Mixtures via a Common Molecular Target Using a Geospatial Modeling Approach | Society of Toxicology |
| 2023 | Krishna S, Chang X, Eccles KM, Messier K, Kleinstreuer NC | Risk-Based, Geospatially Informed Prioritization of Potentially Cardiotoxic Chemicals | Society of Toxicology |
| 2023 | Salminen AT, Davis KJ, Felton RP, Nischal N, VonTungeln LS, Beland FA, Derr K, Brown PC, Ferrer M, Katz LM, Kleinstreuer NC, Leshin J, Manga P, Sadrieh N, Xia M, Fitzpatrick SC, Camacho L | Parallel Evaluation of Alternative Skin Barrier Models and Excised Human Skin for Dermal Absorption Studies In Vitro | Society of Toxicology |
| 2023 | Reynolds G, Reynolds J, Gilmour N, Strickland J, Reinke E, Germolec D, Truax J, Allen D, Maxwell G, Kleinstreuer N | The Skin Allergy Risk Assessment-Integrated Chemical Environment (SARA-ICE) Model for UN GHS Classification: An Evaluation and Application in Case Studies | Society of Toxicology |
| 2023 | Kleinstreuer NC | The Central Role of Computational Toxicology in Toxicology 2.0 | Society of Toxicology |
| 2022 | Mansouri K, Martin T, Chang X, Allen D, Williams A, Kleinstreuer N | OPERA Models to Support Regulatory Needs | American Society for Cellular and Computational Toxicology |
| 2022 | Hull V, Borrel A, Karmaus AL, To K, Allen D, Kleinstreuer NC | Integration of Technological Interference into the Interpretation of Curated High-throughput Screening (cHTS) Data | American Society for Cellular and Computational Toxicology |
| 2022 | Karmaus AL, Daniel A, Hull V, Reinke E, Medvedev A, Allen D, Kleinstreuer NC, Casey W | Investigating the Impact of Cytochrome P450 Metabolism on Chemical-mediated Transcription Factor Transactivation | American Society for Cellular and Computational Toxicology |
| 2022 | Rogers B, Brown J, Allen D, Casey W, Clippinger A | Progress Towards the Replacement of In Vivo Leptospirosis Vaccine Potency Testing in the United States | American Society for Cellular and Computational Toxicology |
| 2022 | Moreira-Filho JT, Conway M, Schmitt C, Kleinstreuer N, Mansouri K | Chemical Grouping Using an Automated KNIME Workflow: An Interpretable Machine Learning Approach | American Society for Cellular and Computational Toxicology |
| 2022 | Hines D, Cook B, Hull V, Allen D, Dorne JLCM, Erickson J, Combs P, Ferguson S, Kleinstreuer N, Mansouri K | Integrating Population Enzyme Variability Into Physiologically-based Kinetic Models of Parent Chemicals and Metabolites | American Society for Cellular and Computational Toxicology |
| 2022 | Lee S, Li T, Liu Z, Tong W, Mansouri K, Kleinstreuer N | Applying Deep Learning Toxicity Models Across the Chemical Universe | American Society for Cellular and Computational Toxicology |
| 2022 | Strickland J, Abedini J, Allen D, Api AM, Germolec D, Gordon J, Hull V, Kleinstreuer N, Ko HS, Matheson J, Thierse HJ, To K, Truax J, Vanselow JT, Herzler M | Evaluation of Skin Sensitization Classification Rules to Reflect Human Potency and Support Weight-of-Evidence Assessments | American Society for Cellular and Computational Toxicology |
| 2022 | Daniel A, Kleinstreuer N, Allen D, Glover K, Goralski T, Gough B, Schurdak M, Sprankle C, Tagle D, Williams M, Holmes A | Facilitating Global Connections through the Microphysiological Systems for COVID Research (MPSCoRe) Working Group | American Society for Cellular and Computational Toxicology |
| 2022 | van der Zalm AJ, Barroso J, Browne P, Casey W, Henry T, Kleinstreuer NC, Lowit A, Perron M, Clippinger AJ | A Modern Framework to Establish Scientific Confidence in NAMs | American Society for Cellular and Computational Toxicology |
| 2022 | Chang X, Palmer J, Donley E, Reinke E, Allen D, Kleinstreuer N | In Vitro to In Vivo Extrapolation to Facilitate the Animal-free Risk Assessment of Potential Developmental Toxicants | American Society for Cellular and Computational Toxicology |
| 2022 | To K, Karmaus A, Hull V, Allen D, Kleinstreuer N | Characterizing the Impacts of Assay Design on Cytotoxic Concentration Range | American Society for Cellular and Computational Toxicology |
| 2022 | Unnikrishnan A, Chang X, To K, Abedini J, Cook B, Hines D, McAfee E, Phillips J, Allen D, Kleinstreuer N | ICE Tools to Facilitate PBPK Modeling and IVIVE for Various Exposure Scenarios | American Society for Cellular and Computational Toxicology |
| 2022 | Bisson W, Mansouri K, Garner S, Arroyave W, Ewens A, Wang A, Jahnke G, Lunn R | A Potential Novel Integrative Strategy for Read-Across to Evaluate Large Numbers of Nitro-Polycyclic Aromatic Hydrocarbons (NPAHs) for Cancer Hazard Evaluation | American Society for Cellular and Computational Toxicology |
| 2022 | Ehrlich D, Krishna S, Kleinstreuer N | Data-Driven Derivation of an Adverse Outcome Pathway Linking VEGF and Cardiotoxicity | American Society for Cellular and Computational Toxicology |
| 2022 | Chang X, Bell S, Abedini J, Allen D, Kleinstreuer N | Fit for Purpose Evaluation of In Vitro Assays for IVIVE | FutureTox V |
| 2022 | Karmaus AL, Ceger P, Rooney J, Bell S, Allen D, Kleinstreuer N | Developing In Vitro Assay Annotations to Provide Context and Facilitate Interpretation Toward Toxicological Endpoints | FutureTox V |
| 2022 | Hines D, Abedini J, Allen D, Kleinstreuer N, Mansouri K | Integrating Parameter Uncertainty in PBPK Modeling | FutureTox V |
| 2022 | Mumtaz M, Chang X, Allen DG, Kleinstreuer N | Application of In Vitro to In Vivo Extrapolation (IVIVE) to Informing In Vivo Point of Departure | Society of Toxicology |
| 2022 | Strickland J, Truax J, Corvaro M, Settivari R, Henriquez J, Germolec D, Gehen S, Allen D, Kleinstreuer N | Application of Defined Approaches for Skin Sensitization to Agrochemical Products | Society of Toxicology |
| 2022 | Krishna S, Berridge B, Kleinstreuer NC | High-Throughput Screening to Identify Chemical Cardiotoxic Potential | Society of Toxicology |
| 2022 | Mansouri K, Choksi N, Chang X, Allen D, Kleinstreuer N | OPERA Models for ADME Properties | Society of Toxicology |
| 2022 | Ramaiahgari S, Krishna S, Parham F, Auerbach S, Kleinstreuer N, Beverley B, Merrick A, Berridge B | A Comprehensive In Vitro Approach to Assess Environmental Chemical Hazard on Cardiovascular Diseases | Society of Toxicology |
| 2022 | Ross A, Sedykh A, Gombar V, Kleinstreuer N, Merrick A, Shah R, Casey W | OrbiTox: A Computational Translational Discovery Platform for Data Mining and Read-Across | Society of Toxicology |
| 2022 | Hogberg H | Ontogeny of Neurotransmitter Function as an Endpoint for Developmental Neurotoxicity Assessment | Society of Toxicology |
| 2022 | Hogberg H | Assay Gaps in the Developmental Neurotoxicity (DNT) New Approach Methodologies (NAMs) Battery for Human Health Risk Assessment | Society of Toxicology |
| 2022 | Allen DG, Rooney J, To K, Choksi N, Ceger P, Daniel A, Karmaus AL, Strickland J, Truax J, Casey W, Kleinstreuer N | Variability in Reference Test Method Data and the Impact on NAM Evaluations | Society of Toxicology |
| 2022 | Krishna S, Chang X, Kleinstreuer N | Applying IVIVE to Determine Margins of Exposure for Potentially Cardiotoxic Chemicals | Society of Toxicology |
| 2022 | Karmaus A, Rooney J, Ceger P, Abedini J, Phillips J, Bell S, Allen DG, Kleinstreuer NC | Providing Context to In Vitro High-Throughput Screening Data via Annotation and Visualization Tools | Society of Toxicology |
| 2022 | Abedini J, Cook B, McAfee E, Phillips J, Rooney J, Allen DG, Mansouri K, Kleinstreuer NC | ICE Tools to Support Chemical Evaluations | Society of Toxicology |
| 2022 | Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Choksi N, Daniel A, Hines D, Karmaus AL, McAfee E, Phillips J, Allen DG, Casey W, Kleinstreuer NC | Building Confidence in Alternative Methods through ICE | Society of Toxicology |
| 2022 | Strickland J, To K, Matheson J, Germolec D, Allen DG, Api AM, Gordon J, Ko H, Thierse H, Truax J, Kleinstreuer NC, Herzler M | Variability of Human Reference Data for Skin Sensitization | Society of Toxicology |
| 2022 | Reynolds G, Reynolds J, Gilmour N, Strickland J, Germolec D, Truax J, Maxwell G, Kleinstreuer N | Modification of the Skin Allergy Risk Assessment (SARA) Model for GHS Classification and Its Application to Isothiazolinone Case Studies | Society of Toxicology |
| 2022 | Cook B, Abedini J, Bell S, Rooney J, McAfee E, Phillips J, Allen D, Kleinstreuer N | Providing Context for Chemical Effects Through Compound Structure Similarity | American Chemical Society 2022 Spring Meeting |
| 2021 | Karmaus A, Rooney J, Ceger P, Abedini J, Phillips J, Bell S, Allen D, Kleinstreuer N | Annotating and Visualizing In Vitro Data to Gain Context | American Society for Cellular and Computational Toxicology |
| 2021 | Bishop P, Mansouri K, Allen D, Casey W, Kleinstreuer N | Acute Oral Toxicity Predictions for Environmental Risk Assessment | American Society for Cellular and Computational Toxicology |
| 2021 | Abedini J, Cook B, McAfee E, Phillips J, Bell S, Rooney J, Allen D, Casey W, Kleinstreuer N | Utilizing ICE Tools to Expand Chemical Knowledge: Chemical Quest | American Society for Cellular and Computational Toxicology |
| 2021 | Allen D, Rooney J, Choksi N, Ceger P, Daniel A, Karmaus A, Strickland J, To K, Truax J, Casey W, Kleinstreuer N | Establishing Confidence in NAMs: Considering Variability in Reference Test Methods | American Society for Cellular and Computational Toxicology |
| 2021 | Mansouri K, Chang X, Allen D, Casey W, Kleinstreuer N | QSAR Models Supporting Toxicokinetic Modeling and In Vitro to In Vivo Extrapolation | American Society for Cellular and Computational Toxicology |
| 2021 | Krishna S, Beverley B, Walker V, Kleinstreuer N, Rooney A | Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease | American Society for Cellular and Computational Toxicology |
| 2021 | Krishna S, Borrell A, Huang R, Zhao J, Xia M, Kleinstreuer N | High-throughput Screening to Predict hERG Inhibition | American Society for Cellular and Computational Toxicology |
| 2021 | Chang X, Palmer J, Donley E, Allen D, Casey W, Kleinstreuer N | In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Selected Tox21 Chemicals | American Society for Cellular and Computational Toxicology |
| 2021 | Bell S, Ceger P, Fostel J, Holmgren S, Masci AM, Allen D, Casey W, Kleinstreuer N | Accelerating Adoption of NAMs with FAIR Principles | American Society for Cellular and Computational Toxicology |
| 2021 | Strickland J, Truax J, Corvaro M, Settivari R, Henriquez R, McFadden J, Gulledge T, Johnson V, Gehen S, Germolec D, Allen D, Kleinstreuer N | Skin Sensitization Testing of Mixtures Without Animals | American Society for Cellular and Computational Toxicology |
| 2021 | Rooney J, Abedini J, Bell S, Chang X, Cook B, Ceger P, Hines D, Karmaus A, McAfee E, Phillips J, Allen D, Casey W, Kleinstreuer N | Building Confidence in Alternative Methods Through ICE | American Society for Cellular and Computational Toxicology |
| 2021 | Strickland J, Allen D, Api AM, Gordon J, Kleinstreuer N, Ko HS, Matheson J, Thierse HJ, Truax J, Herzler M | Compilation and Characterization of a Human Skin Sensitization Data Set | American Society for Cellular and Computational Toxicology |
| 2021 | Hines D, Bell S, X Chang, K Mansouri, D Allen, W Casey, N Kleinstreuer | Computational Support of Pharmacokinetic Models and In Vitro to In Vivo Extrapolation | American Society for Cellular and Computational Toxicology |
| 2021 | Strickland J, Daniel A, Allen DG, Kleinstreuer N, Haugabrooks E | International regulatory needs for acute toxicity data | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Kleinstreuer N | Systematic evidence mapping of research on environmental exposures and cardiovascular disease | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Kleinstreuer N | High-throughput screening to predict HERG inhibition | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Foster C, Wignall J, Kovach S, Choksi N, Allen D, Trgovcich J, Rochester J, Ceger P, Daniel A, Hamm J, Truax J, Blake B, McIntyre B, Sutherland V, Stout M, Kleinstreuer N | Standardizing developmental toxicology study extractions using automated application of ontologies | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Hamm J, Allen DG, Ceger P, Flint T, Lowit A, O'Dell L, Tao J, Kleinstreuer N | Performance of the GHS Mixtures Equation for predicting acute oral toxicity | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Sprankle CS, Abedini J, Bell S, Browning L, Daniel A, McAfee E, Phillips J, Allen DG, Kleinstreuer N | Effective user support documentation for a toxicological data resource: ICE as a case study | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Strickland J, Truax J, Corvaro M, Settivari R, Henriquez J, Germolec D, Allen DG, Kleinstreuer N | Application of defined approaches for skin sensitization to agrochemical products | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Rooney JP, Choksi N, Ceger P, Daniel A, Truax J, Allen DG, Kleinstreuer N | Variability in the rabbit skin irritation assay | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Mansouri K | OPERA, an open-source and open-data suite of QSAR models | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Ceger P, Allen DG, Choksi N, Daniel A, Eckel W, Hamm J, Harwood E, Johnson T, Kleinstreuer N, Sprankle C, Truax J, Lowit M | Retrospective evaluation of the acute fish toxicity test for pesticide registration | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Karmaus AL, Mansouri K, Fitzpatrick J, Strickland J, Patlewicz G, Allen DG, Casey W, Kleinstreuer N | Rat acute systemic toxicity testing: evaluating reproducibility and inherent variability | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Choksi N, Clippinger AJ, Gehen S, Corvaro M, Kolle SN, Bentley K, Hofstra A, Inforzato M, Ryan N, Webb E, Casey W, Kleinstreuer N, Allen DG | Developing a defined approach for eye irritation testing | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Allen DG, Rooney JP, Kleinstreuer N, Lowit A, Perron M | Retrospective analysis of dermal triple pack data | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Chang X, Lumen A, Palmer J, Mansouri K, Lee UJ, Ceger P, Donley ELR, Bell S, Allen DG, Casey W, Kleinstreuer N | In vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Bell S, Abedini J, Chang X, Cook B, Hines D, Karmaus AL, McAfee E, Phillips J, Rooney J, Mansouri K, Allen DG, Casey W, Kleinstreuer N | Improving alternative method adoption through tools and resources to support community knowledge | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Kleinstreuer N | Building an AOP-driven defined approach guideline | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Kleinstreuer N | Applying in vitro to in vivo extrapolation to NAM-derived PODs | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Karmaus AL, Hsieh J, Huang R, Shockley K, Paul-Friedman K, Judson R, Casey W, Kleinstreuer N, Sipes N | Comparing and interpreting Tox21 data analysis approaches | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Kleinstreuer N | A North American regulatory perspective on skin sensitization risk assessment | 11th World Congress on Alternatives and Animal Use in the Life Sciences |
| 2021 | Chang X, Lumen A, Palmer J, Mansouri K, Lee UJ, Ceger P, Donley B, Bell S, Allen DG, Casey W, Kleinstreuer NC | In vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues | Society for Birth Defects Research and Prevention |
| 2021 | Cook B, Abedini J, Bell S, McAfee E, Phillips J, Allen D, Kleinstreuer N | Chemical exploration: providing biological context for NAMs | QSAR 2021 |
| 2021 | Mansouri K, Karmaus A, Fitzpatrick J, Patlewicz G, Pradeep P, Allen D, Casey W, Kleinstreuer N | Collaborative modeling project for predicting acute oral toxicity (CATMoS) | QSAR 2021 |
| 2021 | Abedini J, Bell S, Chang X, Choksi N, Cook B, Daniel AB, Hines D, Karmaus AL, Mansouri K, Allen D, Kleinstreuer N | NICEATM computational tools and data resources | QSAR 2021 |
| 2021 | Mansouri K, Grulke C, Judson R, Richard A, Williams A, Kleinstreuer N | Open-source QSAR-ready chemical structure standardization workflow | QSAR 2021 |
| 2021 | Kleinstreuer N | Automated approaches to anchoring alternatives | Society of Toxicology |
| 2021 | Ceger P, Allen DG, Choksi N, Daniel A, Eckel W, Hamm J, Johnson T, Kleinstreuer NC, Lowit M, Sprankle C, Truax J, Odenkirchen E | Retrospective evaluation of the acute fish toxicity test for pesticide registration | Society of Toxicology |
| 2021 | Strickland J, Daniel AB, Allen DG, Kleinstreuer NC, Haugabrooks E | International regulatory needs for acute toxicity data | Society of Toxicology |
| 2021 | Hamm J, Allen DG, Ceger P, Flint T, Kleinstreuer NC, O'Dell L, Tao JJ, Lowit A | Predicting oral acute toxicity using the GHS additivity equation | Society of Toxicology |
| 2021 | Cook B, Abedini JA, Bell S, McAfee E, Phillips J, Rooney JP, Allen DG, Kleinstreuer NC | Providing context for chemical effects through bioactivity and consumer use | Society of Toxicology |
| 2021 | Abedini JA, Bell S, Chang X, Cook BT, Karmaus AL, Mansouri K, Allen DG, Kleinstreuer NC | NICEATM computational tools and resources supporting alternative test method development and evaluation | Society of Toxicology |
| 2021 | Mansouri K, Chang X, Judson R, Williams A, Allen DG, Kleinstreuer NC | OPERA models for ADME properties and toxicity endpoints | Society of Toxicology |
| 2021 | Allen DG, Rooney JP, Kleinstreuer NC, Lowit A, Perron M | Retrospective analysis of dermal absorption triple pack data | Society of Toxicology |
| 2021 | Rooney JP, Choksi N, Ceger P, Daniel AB, Truax J, Allen DG, Kleinstreuer NC | Variability in the rabbit skin irritation assay | Society of Toxicology |
| 2021 | Daniel AB, Abedini JA, Bell S, Chang X, Cook B, Karmaus AL, Hines DE, McAfee E, Phillips J, Rooney JP, Allen DG, Kleinstreuer NC | Updates to the Integrated Chemical Environment: expanding tools and data to support toxicity assessments | Society of Toxicology |
| 2021 | Kleinstreuer N | International regulatory progress on nonanimal approaches for skin sensitization | Society of Toxicology |