Presentations at ASCCT 2023
Twelfth Annual Meeting: American Society for Cellular and Computational Toxicology
October 23-25 - Silver Spring, MD, USA
NICEATM authors in bold; ICCVAM authors in bold italics
Oral Presentations
NAMs as Problem Solvers
Leveraging the Success of the DASS to Establish IATAs for Respiratory Sensitization
Authors: J Ponder, E Reinke, K Sullivan, E Slankster-Schmeirer, R Vandebriel, E Baker
Challenges and Solutions to Implementing NAMs for Regulatory Decision-Making Contexts
Implementing the ICCVAM Roadmap: Establishing Confidence
Author: J Gordon
Integrating NAMs for Better Application
Expanding PBPK Modeling to Predict Chemical Distribution in Brain and Adipose Tissues
Authors: A Unnikrishnan, X Chang, V Hull, GE Tedla, H Hogberg, J Sluka, J Wambaugh, D Allen, N Kleinstreuer
Deriving Benchmark Doses from the Deep Learning Prediction Scores of High-Throughput Toxicology Images
Authors: A Tandon, BE Howard, D Mav, M Balik-Meisner, S Ramaiahgari, S Ferguson, RR Shah, BA Merrick
The SARA-ICE Model for Predicting Skin Sensitizer Potency
Authors: G Maxwell, G Reynolds, J Reynolds, N Gilmour, J Strickland, EN Reinke, D Germolec, J Truax, DG Allen, N Kleinstreuer
New Approaches for Ecological Health Assessment
ChemMaps.com v2.0 - Exploring the Environmental Chemical Universe
Authors: A Borrel, A Unnikrishnan, DG Allen, N Kleinstreuer
Poster Presentations
Deep Learning Profile QSAR Modeling to Impute In Vitro Assay Results and Predict Chemical Carcinogenesis Mechanisms
Authors: A Borrel, AL Karmaus, G Tedla, K Mansouri, T Luechtefeld, R Lunn, A Wang, DG Allen, N Kleinstreuer
View Borrel et al. poster
Web Application to Predict Skin Sensitization Using Defined Approaches
Authors: KT To, J Strickland, E Reinke, A Borrel, J Truax, D Allen, N Kleinstreuer
View To et al. poster
Tri-Culture Human Gut Model for Microplastic and Nanoplastic Absorption Testing
Authors: R Gutierrez, A Barrios, S Cao, E Petersen
Comparative Analysis of Ames Test Outcomes Across Five OECD-Recommended Strain Groups and Their Various Subsets
Authors: VK Gombar, AY Sedykh, AJ Green, RR Shah, KW Witt, W Casey
Evaluation of Skin Sensitization Classification Rules to Reflect Induction Potency in Humans
Authors: M Herzler, KT To, A Unnikrishnan, J Abedini, D Allen, D Germolec, J Gordon, N Kleinstreuer, HS Ko, J Matheson, HJ Thierse, J Truax, J Vanselow, J Strickland
View Herzler et al. poster
Comparison and Standardization of Rat Acute Inhalation Study Data to Support Predictive Modeling
Authors: V Hull, EN Reinke, AB Daniel, KT To, AL Karmaus, DG Allen, K Mansouri, N Kleinstreuer
View Hull et al. poster
Curating Chemical Use Categories and Exposure Predictions to Inform Chemical Assessment
Authors: V Hull, T LaPratt, AL Karmaus, KT To, A Unnikrishnan, DG Allen, NC Kleinstreuer
View Hull et al. poster
Facilitating NAM-Based Chemical Assessments with the Integrated Chemical Environment
Authors: A Unnikrishnan, V Hull, X Chang, A Borrel, K To, A Karmaus, J Phillips, E McAfee, D Allen, N Kleinstreuer
View Unnikrishnan et al. poster
Case Study Application of a Systematic Approach to Inventory and Interrogate Thyroid Hormone Network Information
Authors: IA Lee, SJ Borghoff, D Wikoff, S Fitch, J Urban, C Perry, G Chappell, N Choksi, J Britt, M Heintz, W Klaren, R Chew, S Edwards, RJ Bever, K Hamernik, AB Kirk, SG Lynn, KJ Markey (U.S. Environmental Protection Agency project)
Continuing Education Courses
CE 2: Open-Access Data and Computational Tools to Investigate Chemical Bioactivity
Aswani Unnikrishnan, Victoria Hull, Kim To, and Alexandre Borrel (Inotiv, contractor supporting NICEATM) presented - View presentation
CE 3: Putting Theory Into Practice: Using In Vitro and Computational New Approach Methodologies (NAMs) in Human-Relevant Risk Assessment
Nicole Kleinstreuer (NIEHS/NICEATM) presented.