Presentations at ASCCT 2021

Tenth Annual Meeting: American Society for Cellular and Computational Toxicology – October 12-14, 2021

NICEATM and ICCVAM Oral Presentations 

Oral Session: 21st Century Challenges for 21st-Century Toxicology

Annotating and Visualizing In Vitro Data to Gain Context 
A Karmaus, J Rooney, P Ceger, J Abedini, J Phillips, S Bell, D Allen, N Kleinstreuer

Oral Session: New Approaches to Validation

Establishing Confidence in NAMs: Considering Variability in Reference Test Methods
D Allen, J Rooney, N Choksi, P Ceger, A Daniel, A Karmaus, J Strickland, K To, J Truax, W Casey, N Kleinstreuer

Use of Cause-and-effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air-liquid Interface
E Petersen, M Sharma, A Clippinger, J Gordon, A Katz, P Laux, L Leibrock, A Luch, J Matheson, A Stucki, J Tentschert, F Bierkandt

Acute Oral Toxicity Predictions for Environmental Risk Assessment
P Bishop, K Mansouri, D Allen, W Casey, N Kleinstreuer

Oral Session: Novel Methods or Approaches

Utilizing ICE Tools to Expand Chemical Knowledge: Chemical Quest
Authors: J Abedini, B Cook, E McAfee, J Phillips, S Bell, J Rooney, D Allen, W Casey, N Kleinstreuer

NICEATM and ICCVAM Poster Presentations

Poster Session: Applying Artificial Intelligence in Toxicology

QSAR Models Supporting Toxicokinetic Modeling and In Vitro to In Vivo Extrapolation
K Mansouri, X Chang, D Allen, W Casey, N Kleinstreuer

Machine Learning Comparison for Hepatoxicity Predictions Using Targeted Transcriptomic and Chemical Structure Data
Authors: T Tate, G Patlewicz, I Shah

Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease
Authors: S Krishna, B Beverley, V Walker, N Kleinstreuer, A Rooney

High-throughput Screening to Predict hERG Inhibition
Authors: S Krishna, A Borrell, R Huang, J Zhao, M Xia, N Kleinstreuer

Poster Session: New Approaches to Validation

In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Selected Tox21 Chemicals
X Chang, J Palmer, E Donley, D Allen, W Casey, N Kleinstreuer
View Chang et al. poster

Accelerating Adoption of NAMs with FAIR Principles
S Bell, P Ceger, J Fostel, S Holmgren, AM Masci, D Allen, W Casey, N Kleinstreuer
View Bell et al. poster

Poster Session: 21st Century Challenges

Skin Sensitization Testing of Mixtures Without Animals
J Strickland, J Truax, M Corvaro, R Settivari, J Henriquez, J McFadden, T Gulledge, V Johnson, S Gehen, D Germolec, D Allen, N Kleinstreuer
View Strickland et al. poster

OrbiTox – A Translational Discovery Platform for Concerted View and Analysis of Multi-domain Data
Authors: V Gombar, A Sedykh, A Ross, K Witt, R Shah, W Casey

Building Confidence in Alternative Methods Through ICE
J Rooney, J Abedini, S Bell, X Chang, B Cook, P Ceger, D Hines, A Karmaus, E McAfee, J Phillips, D Allen, W Casey, N Kleinstreuer
View Rooney et al. poster

Compilation and Characterization of a Human Skin Sensitization Data Set
J Strickland, D Allen, AM Api, J Gordon, N Kleinstreuer, HS Ko, J Matheson, HJ Thierse, J Truax, M Herzler
View Strickland et al. poster

Computational Support of Pharmacokinetic Models and In Vitro to In Vivo Extrapolation
D Hines, S Bell, X Chang, K MansouriD Allen, W Casey, N Kleinstreuer
View Hines et al. poster