ICCVAM Public Forum: May 2023

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): advancing alternatives to animal testing

May 18-19, 2023

National Institutes of Health, Bethesda, MD and online

Presentation slides are available below.

ICCVAM’s goals include promotion of national and international partnerships between governmental and nongovernmental groups, including academia, industry, advocacy groups, and other key stakeholders. To foster these partnerships ICCVAM holds annual public forums to share information and facilitate direct communication of ideas and suggestions from stakeholders.

This event was held in person at the National Institutes of Health in Bethesda, MD, with an option for remote viewing. Representatives of ICCVAM member agencies described their agencies' activities both to advance new approaches to safety testing of chemicals and medical products and to reduce the amount of testing required. Registered participants were able to ask clarifying or follow-up questions of the ICCVAM members about their presentations during the meeting. Six ICCVAM stakeholders presented public oral statements relevant to the ICCVAM mission and current activities.


Welcome and Introductions: Anna Lowit, EPA, ICCVAM co-chair

CPSC Guidance on NAMs: John Gordon, CPSC, ICCVAM co-chair

Update from EPA Office of Pesticide Programs: Monique Perron, EPA

Update from EPA Office of Pollution Prevention and Toxics: Anna Lowit, EPA

Update on Advancing Alternatives for Regulatory Use: Suzanne Fitzpatrick, FDA

Update on GHS Non-Animal Testing: Deana Holmes, OSHA

Update on NAMs Efforts at VA: George Lathrop, VA Office of Research and Development

Update on OECD and Other International Activities: Charles Kovatch, EPA

Alternative Approaches to Ecotoxicological Testing and Assessment: Jessica Leet, DOI

Measurement Science in ICCVAM: Elijah Petersen, NIST

In Vitro Co-Culture Assays to Assess Safety of CAR-T Cell Therapies: Shari Price, Leidos Biomedical Research (contractor supporting NCI)

NICEATM Computational Tools Update: Kamel Mansouri, NIEHS

Public Comments Presented During Meeting:

NICEATM and NIEHS Update: Nicole Kleinstreuer, NIEHS

ICCVAM Workgroup Updates: David Allen, Inotiv (contractor supporting NICEATM)

Animal Welfare Information Center: Jessie Carder, USDA

Advancing NAMs to Support Regulatory Toxicology Evaluations of Tobacco Products: Luis Valerio, FDA

Soldier-on-a-Chip - Interrogating the Effects of Chemical and Biological Threat Agent Exposure Using a Multi-Organ MPS: Tyler Goralski, DoD

Tissue Chips for Drug Screening Program: Danilo Tagle, NIH/NCATS

Public Comments

Cruelty Free International (May 12)

Physicians Committee for Responsible Medicine (May 12)

People for the Ethical Treatment of Animals (May 11)

Humane Society of the United States/Humane Society Legislative Fund (May 9)