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ICCVAM Public Forum: May 2021

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): advancing alternatives to animal testing

Webcast: May 27, 2021

ICCVAM’s goals include promotion of national and international partnerships between governmental and nongovernmental groups, including academia, industry, advocacy groups, and other key stakeholders. To foster these partnerships ICCVAM holds annual public forums to share information and facilitate direct communication of ideas and suggestions from stakeholders.

Usually an in-person event, the 2021 public forum was presented as a webinar. Representatives of ICCVAM member agencies described activities both to advance new approaches to safety testing of chemicals and medical products and to reduce the amount of testing required.

Video: morning session (approx. 2 hr, 36 min)

Video: afternoon session (approx. 3 hr, 18 min)

Presentations

Welcome and Introductions: Anna Lowit, EPA, and Emily Reinke, DoD, ICCVAM Co-chairs

NICEATM and NTP Update: Nicole Kleinstreuer, NIEHS

ICCVAM Workgroup Updates: David Allen, ILS (contractor supporting NICEATM)

Consumer Product Safety Commission Guidance for Industry and Test Method Developers: John Gordon, CPSC

USDA Animal Welfare Information Center: Jessie Kull, USDA

Application of NAMs, Surrogates, and Read-across in Rapid Development of PBPK Models for Human Health Risk Assessment: Lisa Sweeney, DoD

Investigation of Parathion-induced Neurotoxicity in SHSY5Y Cells Demonstrates Utility of the Assay as an Alternative Animal Model: Saroj Amar, DoD

Assessment of Acute Oral Toxicity for Mixtures Using In Silico Modeling Methods: Matthew Linakis, DoD

Alternative Approaches to Ecotoxicological Testing and Assessment: Barnett Rattner, U.S. Department of the Interior

Impact of Alternatives to Animals in VA Research: George Lathrop, U.S. Department of Veterans Affairs Office of Research and Development (presentation not available)

Update on EPA ORD New Approach Method Research Activities: Rusty Thomas, EPA Office of Research and Development

Recent Progress Towards Reducing Animal Use & Adopting NAMs at EPA's Office of Pesticide Programs: William Eckel, EPA Office of Pesticide Programs

OPPT's Progress Implementing the Near-term Activities in the TSCA Strategic Plan: Tala Henry, EPA Office of Pollution Prevention and Toxics

Advancing Alternative Methods at FDA: Suzanne Fitzpatrick, FDA

Measurement Science Activities Under ICCVAM: Elijah Petersen, National Institute of Standards and Technology

OECD Test Guidelines Programme Update: Charles Kovatch, EPA

Public Comments Presented During Meeting

    • Ahimsa Porter Sumchai, Hunters Point Community Biomonitoring Program
    • Katherine Groff, People for the Ethical Treatment of Animals
    • Jessica Ryman-Rasmussen, American Petroleum Institute
    • Elizabeth Donley, Stemina Biomarker Discovery
      Presentation: ICCVAM Public Statement
    • Kristie Sullivan, Physicians Committee for Responsible Medicine
    • Laura Alvarez, Cruelty Free International
      Presentation: Making Alternatives a Priority (MAP)
    • Vicki Katrinak, Humane Society of the United States
    • Amy Kyle, University of California – Berkeley
    • Hans Raabe, Institute for In Vitro Sciences
Public Comments

Humane Society of the United States/Humane Society Legislative Fund (May 13)

People for the Ethical Treatment of Animals (May 20)

American Petroleum Institute (May 21)

Physicians Committee for Responsible Medicine (May 21)