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https://ntp.niehs.nih.gov/go/ascct-2021

Presentations at ASCCT 2021

Tenth Annual Meeting: American Society for Cellular and Computational Toxicology – October 12-14, 2021

Virtual meeting: view full program

NICEATM and ICCVAM Oral Presentations 

Oral Session: 21st Century Challenges for 21st-Century Toxicology

Tuesday, October 12, 10:15 a.m.-12:15 p.m. EDT

Annotating and Visualizing In Vitro Data to Gain Context 
Authors: 
A Karmaus, J Rooney, P Ceger, J Abedini, J Phillips, S Bell, D Allen, N Kleinstreuer

Oral Session: New Approaches to Validation

Thursday, October 14, 10:00 a.m.-12:00 noon EDT

Establishing Confidence in NAMs: Considering Variability in Reference Test Methods
Authors: 
D Allen, J Rooney, N Choksi, P Ceger, A Daniel, A Karmaus, J Strickland, K To, J Truax, W Casey, N Kleinstreuer

Use of Cause-and-effect Analysis to Optimize the Reliability of In Vitro Inhalation Toxicity Measurements Using an Air-liquid Interface
Authors: 
E Petersen, M Sharma, A Clippinger, J Gordon, A Katz, P Laux, L Leibrock, A Luch, J Matheson, A Stucki, J Tentschert, F Bierkandt

Acute Oral Toxicity Predictions for Environmental Risk Assessment
Authors: 
P Bishop, K Mansouri, D Allen, W Casey, N Kleinstreuer

Oral Session: Novel Methods or Approaches

Thursday, October 14, 12:00 noon-1:00 p.m. EDT

Utilizing ICE Tools to Expand Chemical Knowledge: Chemical Quest
Authors: J Abedini, B Cook, E McAfee, J Phillips, S Bell, J Rooney, D Allen, W Casey, N Kleinstreuer

NICEATM and ICCVAM Poster Presentations

Poster Session: Applying Artificial Intelligence in Toxicology

Wednesday, October 13, 1:30-3:30 p.m. EDT

QSAR Models Supporting Toxicokinetic Modeling and In Vitro to In Vivo Extrapolation
Authors: 
K Mansouri, X Chang, D Allen, W Casey, N Kleinstreuer
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

Machine Learning Comparison for Hepatoxicity Predictions Using Targeted Transcriptomic and Chemical Structure Data
Authors: T Tate, G Patlewicz, I Shah

Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease
Authors: S Krishna, B Beverley, V Walker, N Kleinstreuer, A Rooney

High-throughput Screening to Predict hERG Inhibition
Authors: S Krishna, A Borrell, R Huang, J Zhao, M Xia, N Kleinstreuer

Poster Session: New Approaches to Validation

Wednesday, October 13, 1:30-3:30 p.m. EDT

In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Selected Tox21 Chemicals
Authors: 
X Chang, J Palmer, E Donley, D Allen, W Casey, N Kleinstreuer
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

Accelerating Adoption of NAMs with FAIR Principles
Authors: 
S Bell, P Ceger, J Fostel, S Holmgren, AM Masci, D Allen, W Casey, N Kleinstreuer
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

Poster Session: 21st Century Challenges

Thursday, October 14, 1:30-3:30 p.m. EDT

Skin Sensitization Testing of Mixtures Without Animals
Authors: 
J Strickland, J Truax, M Corvaro, R Settivari, J Henriquez, J McFadden, T Gulledge, V Johnson, S Gehen, D Germolec, D Allen, N Kleinstreuer
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

OrbiTox – A Translational Discovery Platform for Concerted View and Analysis of Multi-domain Data
Authors: V Gombar, A Sedykh, A Ross, K Witt, R Shah, W Casey
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

Building Confidence in Alternative Methods Through ICE
Authors: 
J Rooney, J Abedini, S Bell, X Chang, B Cook, P Ceger, D Hines, A Karmaus, E McAfee, J Phillips, D Allen, W Casey N Kleinstreuer
Featured in a 3-minute flash presentation (session Tuesday, October 12, 2:20-3:30 p.m.)

Compilation and Characterization of a Human Skin Sensitization Data Set
Authors:
J Strickland, D Allen, AM Api, J Gordon, N Kleinstreuer, HS Ko, J Matheson, HJ Thierse, J Truax, M Herzler

Computational Support of Pharmacokinetic Models and In Vitro to In Vivo Extrapolation
Authors:
D Hines, S Bell, X Chang, K MansouriD Allen, W Casey, N Kleinstreuer