Skip to Main Navigation
Skip to Page Content
COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Presentations at 11th World Congress on Alternatives and Animal Use

August 23-September 2, 2021

Visit meeting website


Oral Presentations

S111: Modern, Mechanistic Approaches to Cancer Risk Assessment

Abstract Number 11: Modernizing the NTP's Carcinogenicity Testing Program
Speaker: W Casey (ICCVAM member, NIEHS)

S126: Modern Regulatory Methods for Skin Sensitization: Bye-Bye Buehler?

Abstract Number 48: A North American Regulatory Perspective on Skin Sensitization Risk Assessment
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S205: A Virtual Human Platform for Safety Assessment

Abstract Number 1000: Comparing and Interpreting Tox21 Data Analysis Approaches
Speaker: A Karmaus (ILS, contractor supporting NICEATM)

S160: Human Organs-on-Chips: Advancing Regulatory Science Through Innovation

Suzanne Fitzpatrick (ICCVAM member, FDA) was session chair.

Abstract Number 946: Developing Performance Based Qualification Criteria for Organs on a Chip
Speaker: S Fitzpatrick (ICCVAM member, FDA)

S60: New Approach Methods in AgroChemical Development and Regulatory Decisions

Abstract Number 68: Waiving Repeat Dose Studies While Confidently Protecting Human Health from Exposure to Agricultural Chemicals
Speaker: M Perron (ICCVAM workgroup member, EPA)

S181: Use of New Approach Methodologies - NAMs - to Derive Point(s) of Departure; Opportunities and Limitations

Abstract Number 49: Applying In Vitro to In Vivo Extrapolation to NAM-derived PODs
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S315: EPAA Training Session on Skin Sensitisation

Keynote Introduction to Skin Sensitisation NAMs and Defined Approaches
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S59: Innovative Technologies Integrating Standardised Regulatory Test Methods: Challenges and Perspectives

Abstract Number 297: Integrating Innovative Methods to Predict a Regulatory Hazard Endpoint: a Regulatory Perspective
Speaker: M Perron (ICCVAM workgroup member, EPA)

S104: AOPs, MOAs, and KCs - Mutually Informative, Not Mutually Exclusive

Abstract Number 47: Building an AOP-Driven Defined Approach Guideline
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S26: "Proof in Animals": Has Journal Editorial Policy Fallen Behind Advances in Human-based Approaches

Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S313: Roadmap

Abstract Number 1008: Improving Alternative Method Adoption Through Tools and Resources to Support Community Knowledge
Speaker: S Bell (ILS, contractor supporting NICEATM)

S312: QIVIVE

N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS) was session chair.

Abstract Number 442: In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Valproic Acid Analogues
Speaker: X Chang (ILS, contractor supporting NICEATM)


Poster Presentations

Abstract P225: Retrospective Analysis of Dermal Triple Pack Data
Presenter: DG Allen (ILS, contractor supporting NICEATM)
View poster

Abstract P230: Mixture-based QSAR Models of Ocular Toxicity for Regulatory Hazard Categories
Presenter: A Sedykh (Sciome, contractor supporting NICEATM)
View poster

Abstract P232: Rat Acute Systemic Toxicity Testing: Evaluating Reproducibility and Inherent Variability
Presenter: A Karmaus (ILS, contractor supporting NICEATM)
View poster

Abstract P268: Retrospective Evaluation of the Acute Fish Toxicity Test for Pesticide Registration
Presenter: P Ceger (ILS, contractor supporting NICEATM)
View poster

Abstract P505: Developing a Defined Approach for Eye Irritation Testing
Presenter: N Choksi (ILS, contractor supporting NICEATM)
View poster

Abstract P508: OPERA, an Open-source and Open-data Suite of QSAR Models
Presenter: K Mansouri (NIEHS/NICEATM)

Abstract P509: Variability in the Rabbit Skin Irritation Assay
Presenter: JP Rooney (ILS, contractor supporting NICEATM)
View poster

Abstract P511: Application of Defined Approaches for Skin Sensitization to Agrochemical Products
Presenter: J Strickland (ILS, contractor supporting NICEATM)
View poster

Abstract P513: Effective User Support Documentation for a Toxicological Data Resource: ICE as a Case Study
Presenter: C Sprankle (ILS, contractor supporting NICEATM)
View poster

Abstract P572: Performance of the GHS Mixtures Equations for Predicting Acute Oral Toxicity
Presenter: J Hamm (ILS, contractor supporting NICEATM)
View poster

Abstract P576: Standardizing Developmental Toxicology Study Extractions Using Automated Application of Ontologies
Presenter: C Foster (ICF; collaboration with NICEATM)

Abstract P577: High-throughput Screening to Predict HERG Inhibition
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Abstract P578: Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Abstract P586: International Regulatory Needs for Acute Toxicity Data
Presenter: J Strickland (ILS, contractor supporting NICEATM)
View poster