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Presentations at 11th World Congress on Alternatives and Animal Use

August 23-September 2, 2021

Information about the meeting: virtual event platform opens Tuesday, August 10


Oral Presentations

Monday, August 23

S111: Modern, Mechanistic Approaches to Cancer Risk Assessment – 1:00-3:00 p.m. EDT

Abstract Number 11: Modernizing the NTP's Carcinogenicity Testing Program
Speaker: W Casey (ICCVAM member, NIEHS)

Tuesday, August 24

S126: Modern Regulatory Methods for Skin Sensitization: Bye-Bye Buehler? – 9:00-11:00 a.m. EDT

Abstract Number 48: A North American Regulatory Perspective on Skin Sensitization Risk Assessment
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S205: A Virtual Human Platform for Safety Assessment – 12:30-2:30 p.m. EDT

Abstract Number 1000: Comparing and Interpreting Tox21 Data Analysis Approaches
Speaker: A Karmaus (ILS, contractor supporting NICEATM)

Wednesday, August 25

S160: Human Organs-on-Chips: Advancing Regulatory Science Through Innovation – 12:30-2:30 p.m. EDT

Suzanne Fitzpatrick (ICCVAM member, FDA) is session chair.

Abstract Number 946: Developing Performance Based Qualification Criteria for Organs on a Chip
Speaker: S Fitzpatrick (ICCVAM member, FDA)

S60: New Approach Methods in AgroChemical Development and Regulatory Decisions – 12:30-2:30 p.m. EDT

Abstract Number 68: Waiving Repeat Dose Studies While Confidently Protecting Human Health from Exposure to Agricultural Chemicals
Speaker: M Perron (ICCVAM workgroup member, EPA)

Thursday, August 26

S181: Use of New Approach Methodologies - NAMs - to Derive Point(s) of Departure; Opportunities and Limitations – 9:00-11:00 a.m. EDT

Abstract Number 49: Applying In Vitro to In Vivo Extrapolation to NAM-derived PODs
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Friday, August 27

S315: EPAA Training Session on Skin Sensitisation – 9:00-11:00 a.m. EDT

Keynote Introduction to Skin Sensitisation NAMs and Defined Approaches
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Monday, August 30

S59: Innovative Technologies Integrating Standardised Regulatory Test Methods: Challenges and Perspectives – 9:00-11:00 a.m. EDT

Abstract Number 297: Integrating Innovative Methods to Predict a Regulatory Hazard Endpoint: a Regulatory Perspective
Speaker: M Perron (ICCVAM workgroup member, EPA)

S104: AOPs, MOAs, and KCs - Mutually Informative, Not Mutually Exclusive – 9:00-11:00 a.m. EDT

Abstract Number 47: Building an AOP-Driven Defined Approach Guideline
Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Tuesday, August 31

S26: "Proof in Animals": Has Journal Editorial Policy Fallen Behind Advances in Human-based Approaches – 9:00-11:00 a.m. EDT

Speaker: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

S313: Roadmap– 9:00-11:00 a.m. EDT

Abstract Number 1008: Improving Alternative Method Adoption Through Tools and Resources to Support Community Knowledge
Speaker: S Bell (ILS, contractor supporting NICEATM)

Wednesday, September 1

S312: QIVIVE– 12:30-2:30 p.m. EDT

N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS) is session chair.

Abstract Number 442: In Vitro to In Vivo Extrapolation for Developmental Toxicity Potency of Valproic Acid Analogues
Speaker: X Chang (ILS, contractor supporting NICEATM)


Poster Presentations

Posters will be viewable on the meeting website from Tuesday, August 10, through Thursday, September 2. Posters will be attended by presenters during two dedicated poster sessions:

  • Friday, August 27: noon-1:30 p.m. EDT
  • Tuesday, August 31: 11:15 a.m.-12:15 p.m. EDT

Abstract P225: Retrospective Analysis of Dermal Triple Pack Data
Presenter: DG Allen (ILS, contractor supporting NICEATM)

Abstract P230: Mixture-based QSAR Models of Ocular Toxicity for Regulatory Hazard Categories
Presenter: N Choksi (ILS, contractor supporting NICEATM)

Abstract P232: Rat Acute Systemic Toxicity Testing: Evaluating Reproducibility and Inherent Variability
Presenter: A Karmaus (ILS, contractor supporting NICEATM)

Abstract P268: Retrospective Evaluation of the Acute Fish Toxicity Test for Pesticide Registration
Presenter: P Ceger (ILS, contractor supporting NICEATM)

Abstract P505: Developing a Defined Approach for Eye Irritation Testing
Presenter: N Choksi (ILS, contractor supporting NICEATM)

Abstract P508: OPERA, an Open-source and Open-data Suite of QSAR Models
Presenter: K Mansouri (NIEHS/NICEATM)

Abstract P509: Variability in the Rabbit Skin Irritation Assay
Presenter: JP Rooney (ILS, contractor supporting NICEATM)

Abstract P511: Application of Defined Approaches for Skin Sensitization to Agrochemical Products
Presenter: J Strickland (ILS, contractor supporting NICEATM)

Abstract P513: Effective User Support Documentation for a Toxicological Data Resource: ICE as a Case Study
Presenter: C Sprankle (ILS, contractor supporting NICEATM)

Abstract P572: Performance of the GHS Mixtures Equations for Predicting Acute Oral Toxicity
Presenter: J Hamm (ILS, contractor supporting NICEATM)

Abstract P576: Standardizing Developmental Toxicology Study Extractions Using Automated Application of Ontologies
Presenter: C Foster (ICF; collaboration with NICEATM)

Abstract P577: High-throughput Screening to Predict HERG Inhibition
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Abstract P578: Systematic Evidence Mapping of Research on Environmental Exposures and Cardiovascular Disease
Presenter: N Kleinstreuer (Acting NICEATM Director; ICCVAM member, NIEHS)

Abstract P586: International Regulatory Needs for Acute Toxicity Data
Presenter: J Strickland (ILS, contractor supporting NICEATM)