NICEATM Abstracts Published Since 2021
| Year Presented | Authors | Title | Presentation Venue |
|---|---|---|---|
| Filter by Year: | |||
| 2025 | Cuomo D, Karmaus A, Hill B, Feshuk M, Osborne G, Blake B, Druwe I, Wang A, Rigutto G, McHale C, Smith MT, Facchin C, De Conti A, Madia F, Kleinstreuer N, Chiu WA, Borrel A | Mapping ToxCast/Tox21 High-throughput Screening Assay Endpoints to Key Characteristics of Carcinogens | Society of Toxicology |
| 2025 | Hill B, Hamm J, Hsieh JH, Reinke EN, Hogberg HT, Ryan K | Understanding the Range of Phenotypic Responses for the Embryonic Zebrafish Developmental Toxicity Assay | Society of Toxicology |
| 2025 | Kreutz A, Karmaus AL, Oyetade OB, Paul Friedman K, Allen DG, Reinke EN, Paparella M, Kleinstreuer NC | Quantifying the Reproducibility and Variability of In Vivo Guideline Toxicology Studies | Society of Toxicology |
| 2025 | Unnikrishnan A, To KT, Herzler M, Germolec D, Reinke E, Kleinstreuer N | Web Application to Classify and Subcategorize Skin Sensitizers Using Human Data | Society of Toxicology |
| 2025 | Ranganath D, Moreira-Filho JT, Collins BJ, Waidyanatha S, Casey W, Kleinstreuer N, Mansouri K | Democratizing cheminformatics: case studies using the MoVIZ pipeline for automated chemical grouping and toxicological insights | Society of Toxicology |
| 2025 | Sakamuru S, Sukhawanit R, Wood S, Huang R, Klumpp-Thomas C, Simeonov A, Kleinstreuer N, Knudsen TB, Xia M | Inhibitors of Cytochrome P450 26A1 identified from screening the Tox21 10K compound library | Society of Toxicology |
| 2025 | Scheufen Tieghi R | DeTox: An in silico alternative to animal testing for predicting developmental toxicity potential | Society of Toxicology |
| 2025 | Kruetz A | In vitro to in vivo extrapolation application for assessing developmental neurotoxicity | Society of Toxicology |
| 2025 | Modaresi S, Salminen AT, Davis KJ, Felton RP, Sun J, Beland FA, Derr K, Brown PC, Ferrer M, Katz LM, Kleinstreuer NC, Leshin J, Manga P, Sadrieh N, Xia M, Fitzpatrick SC, Camacho L | Evaluation and comparison of in vitro permeation testing (IVPT) and barrier function in alternative skin models and excised human skin | Society of Toxicology |
| 2025 | Ehrlich D, Krishna S, Kleinstreuer N | Data-driven derivation of an adverse outcome pathway linking vascular endothelial growth factor receptor (VEGFR), endocrine disruption, and atherosclerosis | Society of Toxicology |
| 2025 | Hogberg H | Integrated approaches to testing and assessment case study of mifepristone to determine developmental neurotoxic potential | Society of Toxicology |
| 2025 | Moreira-Filho J, Ranganath D, Tieghi R, Patton R, Sutherland V, Schmitt C, Rooney A, Walker V, Fostel J, Saddler T, Reif D, Mansouri K, Kleinstreuer N | Automating data extraction from scientific literature and general PDF files using large language models and KNIME: An application in toxicology | Society of Toxicology |
| 2025 | Scheufen Tieghi R, Moreira-Filho J, Martin H, Wellnitz J, Otoch MC, Rath M, Tropsha A, Muratov E, Kleinstreuer N | Using ML for human skin sensitization prediction - a novel in silico tool using HPPT data | Society of Toxicology |
| 2025 | Haber L, Bradley MA, Martin EM, Snow SJ, Robertson JM, Fies W, Borrel A, Reinke E, Bevington C, Gordon J, Cho T, Hooker E, Hatlelid K | Class-based hazard and dose-response assessment of polyhalogenated organophosphate flame retardants | Society of Toxicology |
| 2025 | Kleinstreuer N | Building and applying high-confidence computational models in med tech | Society of Toxicology |
| 2025 | Yang S, Knudsen T, Carstens K, Hogberg HT, Xia M | Development of a high-throughput assay platform for neuroinflammation detection using iPSC-derived microglia | Society of Toxicology |
| 2025 | Kleinstreuer N | Advancing one health preparedness: integrating computational dynamic and kinetic systems models into regulatory frameworks | Society of Toxicology |
| 2025 | Tropsha A, Muratov E, Kleinstreuer N | Systemic and topical toxicity (STOPTOX) predictor: model development and external validation | Society of Toxicology |
| 2025 | Krishna S, Chang X, Eccles K, Messier K, Kleinstreuer N | Multiscale risk characterization of chemical cardiotoxicity: integrated in vitro and in silico multiscale modeling reveals cardiovascular risk from chemical exposures | Society of Toxicology |
| 2025 | Chen Y, Salazar K, Mansouri K, Kleinstreuer N | A machine learning approach for predicting inhalation acute toxicity (LC50) values of chemicals using a two-stage regression model | Society of Toxicology |
| 2024 | Marko S, Allen DG, Hogberg H, Oyetade OB, Kleinstreuer NC, Carder J | Opportunities for Encouraging the Consideration of Alternative Methods | Society of Toxicology |
| 2024 | Allen DG, Hull V, Reinke EN, Daniel AB, To KT, Karmaus AL, Mansouri K, Kleinstreuer NC | Curation and Characterization of a Reference Rat Acute Inhalation Toxicity Database | Society of Toxicology |
| 2024 | Borrel A, Tedla G, To KT, Hill B, Karmaus AL, Wang A, Luechtefeld T, Reif D, Allen DG, Kleinstreuer NC | Modern In Vitro Imputation Modeling and Machine Learning to Predict Chemical Carcinogenicity | Society of Toxicology |
| 2024 | Chang X, Palmer J, Donley E, Reinke E, Allen D, Kleinstreuer N | IVIVE to Facilitate Animal-free Risk Assessment of Potential Developmental Toxicants | Society of Toxicology |
| 2024 | Daniel AB, van der Zalm AJ, Raabe HA, Clippinger AJ, Kleinstreuer NC, Allen DG | Predicting GHS Hazard Classification for Eye Irritation/Corrosion Potential of Agrochemical Formulations Using Defined Approaches | Society of Toxicology |
| 2024 | Hill BN, Reinke EN, Auman JT, Unnikrishnan A, Allen DG, Kleinstreuer NC | Incorporating Ontologies into High Throughput Screening Assay Annotations to Increase Data Use and Interpretation | Society of Toxicology |
| 2024 | Hull V, LaPratt TR, Karmaus AL, To KT, Unnikrishnan A, Allen DG, Kleinstreuer NC | Curating chemical use categories and exposure predictions to inform chemical assessment | Society of Toxicology |
| 2024 | Johnson VJ, Reinke EN, LaPratt TR, Strickland J, To KT, Larne O, Johansson H, Forreryd A, Allen DG, Kleinstreuer NC, Germolec DR | Testing of Regulatory-Relevant Chemicals for Skin and Respiratory Sensitization Hazard | Society of Toxicology |
| 2024 | Kreutz A, Chang X, Lawless M, Shafer TJ, Wambaugh JF, Wetmore BA, Allen DG, Hogberg HT | In Vitro to In Vivo Extrapolation for Developmental Neurotoxicity: A Comparison of Physiologically Based Pharmacokinetic Models | Society of Toxicology |
| 2024 | Maxwell G, Reynolds J, Gilmour N, Strickland J, Reinke EN, Germolec D, Truax J, Allen DG, Blaylock M, LaPratt T, Reynolds G, Kleinstreuer N | Application of Skin Allergy Risk Assessment-Integrated Chemical Environment Defined Approach (SARA-ICE DA) to Assess Skin Sensitization Potency of Isothiazolinone Compounds | Society of Toxicology |
| 2024 | Oyetade OB, Chang X, Kreutz A, Hsieh JH, Behl M, Sipes N, Allen DG, Hogberg HT | OPFR Prioritization using the Developmental Neurotoxicity In Vitro Test Battery: An Update to OECD IATA Case Study | Society of Toxicology |
| 2024 | Reinke EN, LaPratt T, Strickland JA, Germolec D, Truax J, Reynolds J, Reynolds G, Gilmour N, Allen DG, Maxwell G, Kleinstreuer NC | Application of the SARA-ICE Skin Sensitization Defined Approach to a Diverse Chemical Set – a Comparative Case Study | Society of Toxicology |
| 2024 | Sullivan K, Reinke E, Macmillan DS, Raabe H, Germolec D, Allen D, Choi E, Filipovska J, Kleinstreuer N | Advancing Flexibility for Defined Approach Guidelines: Developing Performance Standards to Incorporate Alternate Information Sources into the Defined Approach for Skin Sensitization Guideline | Society of Toxicology |
| 2024 | Tedla G, Borrel A, Karmaus A, Hull V, To KT, Auman JT, Allen DG, Kleinstreuer N | Machine learning-based development of cytotoxicity flags within the Tox21/ToxCast assays | Society of Toxicology |
| 2024 | Unnikrishnan A, Chang X, Kreutz A, Hull V, Tedla GE, Hogberg HT, Sluka JP, Wambaugh JF, Allen DG, Kleinstreuer N | PBPK Modeling to Predict Chemical Distribution in Brain and Adipose Tissues | Society of Toxicology |
| 2024 | Hogberg-Durdock H, Hamm J, Borrel A, Karmaus A , Lane T, Unnikrishnan A, Urbina F, Behl M | Identifying Seizure-Inducing Biological Targets: A Collaborative Approach Using AOP Networks, In Vitro Assays, and Computational Tools | Society of Toxicology |
| 2024 | de Aguiar Marciano L, Filipe Costa L, Silva Cardoso N, de Araújo Paula F, Pupin Silvério A, Kleinstreuer N, Martins I | Risk Assessment of Exposure to Triazole Fungicides by Human Biomonitoring and Mechanistic Data | Society of Toxicology |
| 2024 | Borrel A | Deep-Learning Profile QSAR Modeling to Impute In Vitro Assay Results and Predict Chemical Carcinogenesis Mechanisms | Society of Toxicology |
| 2024 | Scheufen Tieghi R, Rath MK, Moreira-Filho JT, Martin H, Beasley J, Hogberg HT, Kleinstreuer N, Muratov E | PregPred: A Model to Predict the Developmental Toxicity Potential of Environmental Chemicals and FDA-Approved Drugs and Cosmetics | Society of Toxicology |
| 2024 | Sutherland V, Hogberg HT, Behl M, Hsieh J, Mansouri K, Mehta S, Roberts G, Ryan K, Taylor KW, Walker N, Walker VR, Witchey S, Rooney AA | Organophosphate Flame Retardants: A Comprehensive Toxicological Assessment | Society of Toxicology |
| 2024 | McPherson CA, Combs P, Cushman J, Erickson J, Hsieh J, Hall L, Hogberg HT, Kendricks K, Sills R | Integrating Screening Level Developmental Neurotoxicity (DNT) Information of Chemicals in a New Approach Methods (NAMs) Battery to Identify Compounds for Future Study | Society of Toxicology |
| 2024 | Hsieh J, Wang Z, Nolte S, Marvel S, Hill B, Hamm J, Roberts G, Schmitt, Ryan K | SEAZIT-DIVER: A Web Application for Integrating and Visualizing Inter-laboratory Data on Substance-Induced Developmental Toxicity Phenotypes in Zebrafish Embryos | Society of Toxicology |
| 2024 | Moreira-Filho J, Ranganath D, Conway M, Waidyanatha S, Collins B, Schmitt C, Kleinstreuer N, Mansouri K | Modeling and Visualization (MoVIZ): Democratizing Cheminformatics with a User-friendly Guided Pipeline | Society of Toxicology |
| 2024 | Whitehead TM, Strickland J, Conduit GJ, Borrel A, Mucs D, Baskerville-Abraham I | Toxicological Data Gap Filling of Ingredients; Comparison of Machine Learning Based Imputation and Traditional QSAR Methods | Society of Toxicology |
| 2024 | Krishna S, Beverly B, Walker VR, Kleinstreuer NC, Hannani A, Whately H, Trgovcich J, Rochester J, Sprowles J, Miller M, Tracy W, Sibrizzi C, Rooney AA | Artificial Intelligence Approaches to Identify and Categorize Health-Relevant Research for Big Questions: Case Study of Cardiovascular Disease and Environmental Exposures | Society of Toxicology |
| 2024 | Lane TR, Snyder S, Harris JS, Hamm J, Urbina F, Unnikrishnan A, Borrel A, Karmaus A , Behl M, Hogberg-Durdock H | Seizure Predictions Using Adverse Outcome Pathway-Based Fast Interpretable Greedy-Tree Sums Modeling | Society of Toxicology |
| 2024 | Chang X | In Vitro to In Vivo Extrapolation Application to Promote the Use of NAMs for Assessing Inhalation Toxicity | Society of Toxicology |
| 2024 | Kleinstreuer N | Cardiotoxicity NAMs Across the Translational Toxicology Pipeline | American Society for Cellular and Computational Toxicology |
| 2024 | Germolec D | GARDAir Testing of Federal Agency Partners Chemicals of Concern | American Society for Cellular and Computational Toxicology |
| 2024 | Hill B, Auman JT, Unnikrishnan A, Karmaus A, Hogberg H, Reinke E, Kleinstreuer N | Incorporating Ontologies into High-Throughput Screening Assay Annotations to Facilitate Interpretation and Increase Data Use | American Society for Cellular and Computational Toxicology |
Showing 1 to 50 of 210 entries