Alimentary System

Esophagus - Hyperkeratosis

    Narrative
    Esophagus - Hyperkeratosis in a female F344/N rat from a chronic study. There are excess, anuclear keratin layers on the surface of the epithelium.
    Esophagus - Hyperkeratosis in a female F344/N rat from a chronic study. There are excess, anuclear keratin layers on the surface of the epithelium.
    Esophagus - Hyperkeratosis in a female F344/N rat from a chronic study (higher magnification of Figure 1). There are excess, anuclear keratin layers on the surface of the epithelium.
    Esophagus - Hyperkeratosis in a female F344/N rat from a chronic study (higher magnification of Figure 1). There are excess, anuclear keratin layers on the surface of the epithelium.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC