Respiratory System

Lung - Vacuolization, Cytoplasmic

    Narrative
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells have vacuolated cytoplasm.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells have vacuolated cytoplasm.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Most of the cells have also lost their cilia.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Most of the cells have also lost their cilia.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells contain clear, intracytoplasmic vacuoles.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells contain clear, intracytoplasmic vacuoles.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells contain clear, intracytoplasmic vacuoles and have lost their cilia.
    Lung, Bronchiole - Vacuolization, Cytoplasmic in a female B6C3F1/N mouse from a chronic study. The bronchiolar epithelial cells contain clear, intracytoplasmic vacuoles and have lost their cilia.

    Authors

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist/NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Darlene Dixon, DVM, PhD, DACVP
    Group Leader
    Molecular Pathogenesis Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Ronald A. Herbert, DVM, PhD
    Group Leader/NTP Pathologist
    Pathology Support Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Lauren M. Staska, DVM, PhD, DACVP
    Senior Pathologist
    WIL Research
    Hillsborough, NC

    Reviewers

    Gary A. Boorman, DVM, PhD, DACVP, DABT, DACLAM
    Pathologist
    Covance Laboratories, Inc.
    Chantilly, VA

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC