Hepatobiliary System

Liver, Hepatocyte - Karyomegaly

    Narrative
    Karyomegaly in a female B6C3F1 mouse from a subchronic study.
    Karyomegaly in a female B6C3F1 mouse from a subchronic study.
    Karyomegaly in a female B6C3F1 mouse from a subchronic study. Arrow indicates enlargement of hepatocyte cytoplasm and nucleus.
    Karyomegaly in a female B6C3F1 mouse from a subchronic study. Arrow indicates enlargement of hepatocyte cytoplasm and nucleus.

    Author

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    John Cullen, VMD, PhD, DACVP, FIATP
    Anatomic Pathology, Professor
    North Carolina State University College of Veterinary Medicine
    Raleigh, NC

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC