Hematopoietic System

Bone Marrow - Infiltration Cellular, Mast Cell

    Narrative
    Bone marrowin a female F344/N rat from a chronic study showing increased mast cells (arrows).
    Bone marrowin a female F344/N rat from a chronic study showing increased mast cells (arrows).
    Bone marrow in a female F344/N rat from a chronic study showing increased mast cells (arrows).
    Bone marrow in a female F344/N rat from a chronic study showing increased mast cells (arrows).
    Bone marrow in a male F344/N rat from a chronic study. Stained with Giemsa, increased numbers of mast cells (arrows) are easily identified by their purple cytoplasmic granules.
    Bone marrow in a male F344/N rat from a chronic study. Stained with Giemsa, increased numbers of mast cells (arrows) are easily identified by their purple cytoplasmic granules.
    Bone marrow in a male F344/N rat from a chronic study (higher magnification of Figure 3). Mast cells are easily identified by their purple cytoplasmic granules.
    Bone marrow in a male F344/N rat from a chronic study (higher magnification of Figure 3). Mast cells are easily identified by their purple cytoplasmic granules.

    Authors

    Michelle C. Cora, DVM, DACVP
    Veterinary Medical Officer
    NTP Clinical Pathologist
    NTP Clinical Pathology Group
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Gregory Travlos, DVM, DACVP
    Group Leader, Clinical Pathology Group
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Reviewers

    Armando R. Irizarry, DVM, PHD, DACVP
    Adjunct Associate Professor of Veterinary Anatomic and Clinical Pathology
    Department of Comparative Pathobiology
    Purdue University College of Veterinary Medicine
    West Lafayette, IN

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC