Special Senses System

Eye, Cornea - Ulcer

    Narrative
    Eye, Cornea - Ulcer in a male B6C3F1 mouse from a subchronic study. There is denudation of all layers of the corneal epithelium (arrow).
    Eye, Cornea - Ulcer in a male B6C3F1 mouse from a subchronic study. There is denudation of all layers of the corneal epithelium (arrow).
    Eye, Cornea - Ulcer in a male B6C3F1 mouse from a subchronic study (higher magnification of Figure 1). All layers of the corneal epithelium have been lost, exposing the underlying stroma (arrow).
    Eye, Cornea - Ulcer in a male B6C3F1 mouse from a subchronic study (higher magnification of Figure 1). All layers of the corneal epithelium have been lost, exposing the underlying stroma (arrow).
    Eye, Cornea - Ulcer in a male F344/N rat from a subchronic study. Large corneal ulcer (bounded by arrows) colonized by numerous coccoid bacteria (white asterisk) and associated with underlying suppurative inflammation (asterisk).
    Eye, Cornea - Ulcer in a male F344/N rat from a subchronic study. Large corneal ulcer (bounded by arrows) colonized by numerous coccoid bacteria (white asterisk) and associated with underlying suppurative inflammation (asterisk).

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC