Cardiovascular System

Blood Vessel - Mineral

    Narrative
    Aorta - Mineral in a male B6C3F1/N mouse from a chronic study. There is mineral in a segment of the aortic intima (arrow).
    Aorta - Mineral in a male B6C3F1/N mouse from a chronic study. There is mineral in a segment of the aortic intima (arrow).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study. The intima of multiple arteries in the heart contains deeply basophilic material (arrows).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study. The intima of multiple arteries in the heart contains deeply basophilic material (arrows).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study (higher magnification of Figure 2). The intima of an artery in the heart contains mineral (arrows).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study (higher magnification of Figure 2). The intima of an artery in the heart contains mineral (arrows).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study. The mineral in the intima appears as basophilic, crystalline material (arrows).
    Heart, Artery - Mineral in a male F344/N rat from a chronic study. The mineral in the intima appears as basophilic, crystalline material (arrows).

    Authors:

    Crystal L. Johnson, DVM, DACVP
    Veterinary Pathologist II
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Paul W. Snyder, DVM, PhD, Diplomate ACVP, Fellow IATP
    Manager, EPL Midwest
    Senior Pathologist
    Experimental Pathology Laboratories, Inc. 
    West Lafayette, IN

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC