Immune System

Lymph Node - Erythrophagocytosis

    Narrative
    Lymph node - Erythrophagocytosis in a female F344/N rat from a chronic study. Numerous macrophages with intracytoplasmic erythrocytes (arrows) and extravasated erythrocytes fill the medullary sinus of this lymph node.
    Lymph node - Erythrophagocytosis in a female F344/N rat from a chronic study. Numerous macrophages with intracytoplasmic erythrocytes (arrows) and extravasated erythrocytes fill the medullary sinus of this lymph node.
    Lymph node - Erythrophagocytosis in a female F344/N rat from a chronic study (higher magnification of Figure 1). Macrophages within the medullary sinus contain variable numbers of erythrocytes and/or pigment within their cytoplasm (arrows).
    Lymph node - Erythrophagocytosis in a female F344/N rat from a chronic study (higher magnification of Figure 1). Macrophages within the medullary sinus contain variable numbers of erythrocytes and/or pigment within their cytoplasm (arrows).

    Authors

    Kristen Hobbie, DVM, PhD
    Principal Pathologist
    Huntingdon Life Sciences
    Peterborough, UK

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Holly M. Kolenda-Roberts, DVM, PhD, DACVP
    Veterinary Pathologist
    SNBL USA
    Everett, WA

    Reviewers

    Jerrold M. Ward, DVM, PhD, DACVP, FIATP
    Veterinary Pathologist
    Global VetPathology
    Montgomery Village, MD

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC