Alimentary System

Tongue - Ulcer

    Narrative
    Tongue - Ulcer in a female F344/N rat from a chronic study. A portion of the keratinized squamous epithelium of the tongue has been lost, exposing the underlying lamina propria.
    Tongue - Ulcer in a female F344/N rat from a chronic study. A portion of the keratinized squamous epithelium of the tongue has been lost, exposing the underlying lamina propria.
    Tongue - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 1). Inflammatory cells are present on the surface of the ulcer and within the underlying lamina propria.
    Tongue - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 1). Inflammatory cells are present on the surface of the ulcer and within the underlying lamina propria.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC