Alimentary System

Oral Mucosa - Ulcer

    Narrative
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study. A portion of the hard palate mucosa is absent (arrow), exposing the underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study. A portion of the hard palate mucosa is absent (arrow), exposing the underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 1). A portion of the hard palate mucosa is absent, exposing the underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 1). A portion of the hard palate mucosa is absent, exposing the underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study. A portion of the hard palate mucosa is absent (arrow), exposing the inflamed underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study. A portion of the hard palate mucosa is absent (arrow), exposing the inflamed underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 3). A portion of the hard palate mucosa is absent (arrow), exposing the inflamed underlying connective tissue.
    Oral mucosa - Ulcer in a female F344/N rat from a chronic study (higher magnification of Figure 3). A portion of the hard palate mucosa is absent (arrow), exposing the inflamed underlying connective tissue.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC