Special Senses System
Eye, Vitreous - Fibrosis
Narrative








Reactive retinal pigment epithelium (RPE) cells may migrate transretinally into the vitreous (Figure 5


Bringmann A, Wiedemann, P. 2009. Involvement of Müller glial cells in epiretinal membrane formation. Graefes Arch Clin Exp Ophthalmol 247:865-883.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/19415318Frame SR, Slone TW. 1966. Nonneoplastic and neoplastic changes in the eye. In: Pathobiology of the Aging Mouse, Vol 2 (Mohr U, Dungworth DL, Capen CC, Carlton WW, Sundberg JP, Ward JM, eds). ILSI Press, Washington, DC, 97-103.
Hogg PA, Grierson I, Hiscott P. 2002. Direct comparison of the migration of three cell types involved in epiretinal membrane formation. Invest Ophthalmol Vis Sci 43:2749-2757.
Full Text: http://tpx.sagepub.com/content/35/2/252.fullMecklenburg L, Schraermeyer U. 2007. An overview on the toxic morphological changes in the retinal pigment epithelium after systemic compound administration. Toxicol Pathol 35:252-267.
Full Text: http://tpx.sagepub.com/content/35/2/252.fullNational Toxicology Program. 1992. NTP TR-407. Toxicology and Carcinogenesis Studies of C.I. Pigment Red 3 (CAS No. 2425-85-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research Triangle Park, NC.
Abstract: https://ntp.niehs.nih.gov/go/7694National Toxicology Program. 1992. NTP TR-415. Toxicology and Carcinogenesis Studies of Polysorbate 80 (CAS No. 9005-65-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research Triangle Park, NC.
Abstract: https://ntp.niehs.nih.gov/go/7710National Toxicology Program. 2001. NTP TR-501. Toxicology and Carcinogenesis Studies of p, p'-Dichlorodiphenyl Sulfone (CAS No. 80-07-9) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research Triangle Park, NC.
Abstract: https://ntp.niehs.nih.gov/go/14880Saika S, Kono-Saika S, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Flanders KC, Yoo J, Anzano M, Liu C-Y, Kao W W-Y, Roberts AB. 2004. Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am J Pathol 164:651-663.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/14742269Smith RS. 2002. Choroid, lens, and vitreous. In: Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods (Smith RS, John SWM, Nishina PM, Sundberg JP, eds). CRC Press Boca Raton, FL, 161-193.
Smith RS, Hawes NL, Chang B, Nishina PM. 2002. Retina. In: Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods (Smith RS, John SWM, Nishina PM, Sundberg JP, eds). CRC Press, Boca Raton, FL, 195-225.
Yoshitomi K, Boorman GA. 1990. Eye and associated glands. In: Pathology of the Fischer Rat: Reference and Atlas (Boorman GA, Eustis SL, Elwell MR, Montgomery CA, MacKenzie WF, eds). Academic Press, San Diego, CA, 239-260.
Abstract: https://www.ncbi.nlm.nih.gov/nlmcatalog/9002563Eye, Vitreous - Fibrosis in a male F344/N rat from a chronic study. There is loose fibrous connective tissue (asterisk) in the vitreous space between a cataractous lens (L) and a detached, degenerate retina (R).
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