Reproductive System, Female

Vagina - Fibrosis

    Narrative
    Vagina - Fibrosis in a female B6C3F1/N mouse from a chronic study. Increased fibrous tissue is present in the vagina wall.
    Vagina - Fibrosis in a female B6C3F1/N mouse from a chronic study. Increased fibrous tissue is present in the vagina wall.
    Vagina - Fibrosis in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There is fibroplasia and mature collagen fibers with associated chronic inflammatory cells.
    Vagina - Fibrosis in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There is fibroplasia and mature collagen fibers with associated chronic inflammatory cells.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC