Cardiovascular System

Blood Vessel - Arteriosclerosis

    Narrative
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study. The tunica media of a large mesenteric muscular artery is thickened.
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study. The tunica media of a large mesenteric muscular artery is thickened.
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). The tunica media of a large mesenteric muscular artery is proliferative and has a hypereosinophilic, glassy appearance (arteriosclerosis).
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). The tunica media of a large mesenteric muscular artery is proliferative and has a hypereosinophilic, glassy appearance (arteriosclerosis).
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). There is proliferation of the tunica media.
    Mesentery, Artery - Arteriosclerosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). There is proliferation of the tunica media.

    Authors:

    Crystal L. Johnson, DVM, DACVP
    Veterinary Pathologist II
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Paul W. Snyder, DVM, PhD, Diplomate ACVP, Fellow IATP
    Manager, EPL Midwest
    Senior Pathologist
    Experimental Pathology Laboratories, Inc. 
    West Lafayette, IN

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC