Nervous System

Brain - Intramyelinic Edema

    Narrative
    Normal appearance of myelin in cerebellar white matter stained with Luxol fast blue and cresyl violet in a control rat.
    Normal appearance of myelin in cerebellar white matter stained with Luxol fast blue and cresyl violet in a control rat.
    Normal appearance of myelin in cerebellar white matter stained with Luxol fast blue and cresyl violet in a control rat (higher magnification of Figure 1).
    Normal appearance of myelin in cerebellar white matter stained with Luxol fast blue and cresyl violet in a control rat (higher magnification of Figure 1).
    Brain, cerebellum-morphologic features of toxin-induced intramyelinic edema in white matter (arrow) stained with Luxol fast blue and cresyl violet in a rat.
    Brain, cerebellum-morphologic features of toxin-induced intramyelinic edema in white matter (arrow) stained with Luxol fast blue and cresyl violet in a rat.
    Brain, cerebellum-morphologic features of toxin-induced intramyelinic edema in white matter (arrow) stained with Luxol fast blue and cresyl violet in a rat (higher magnification of Figure 3).
    Brain, cerebellum-morphologic features of toxin-induced intramyelinic edema in white matter (arrow) stained with Luxol fast blue and cresyl violet in a rat (higher magnification of Figure 3).

    Authors 

    Peter Little, DVM, MS, PhD, DACVP
    Neuropathology Consultant
    Experimental Pathology Laboratories, Inc.  
    Research Triangle Park, NC

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    James P. Morrison, DVM, DACVP
    Scientific Director
    Charles River Laboratories, Pathology Associates
    Research Triangle Park, NC

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC