Cardiovascular System

Heart - Atrophy

    Narrative
    Heart - Atrophy in a male B6C3F1/N mouse from a chronic study. Thinning of the right ventricular wall (arrow) and interventricular septum (arrowheads) is present.
    Heart - Atrophy in a male B6C3F1/N mouse from a chronic study. Thinning of the right ventricular wall (arrow) and interventricular septum (arrowheads) is present.
    Heart - Atrophy in a male B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Atrophy is present in the right ventricular wall (arrow) and interventricular septum (arrowheads).
    Heart - Atrophy in a male B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Atrophy is present in the right ventricular wall (arrow) and interventricular septum (arrowheads).

    Authors:

    Crystal L. Johnson, DVM, DACVP
    Veterinary Pathologist II
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Brian Berridge, DVM, PhD, DACVP
    Director, WW Animal Research Strategy
    GlaxoSmithKline R&D
    Research Triangle Park, NC

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC