Cardiovascular System

Blood Vessel - Pigment

    Narrative
    Mesentery, Artery - Pigment in a male F344/N rat from a chronic study. Brown pigment is present in the wall of the artery (arrows).
    Mesentery, Artery - Pigment in a male F344/N rat from a chronic study. Brown pigment is present in the wall of the artery (arrows).
    Mesentery, Artery - Pigment in a male F344/N rat from a chronic study (higher magnification of Figure 1). Macrophages containing brown pigment consistent with hemosiderin (arrows) are present in the arterial wall.
    Mesentery, Artery - Pigment in a male F344/N rat from a chronic study (higher magnification of Figure 1). Macrophages containing brown pigment consistent with hemosiderin (arrows) are present in the arterial wall.

    Authors:

    Crystal L. Johnson, DVM, DACVP
    Veterinary Pathologist II
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Paul W. Snyder, DVM, PhD, Diplomate ACVP, Fellow IATP
    Manager, EPL Midwest
    Senior Pathologist
    Experimental Pathology Laboratories, Inc. 
    West Lafayette, IN

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC