Alimentary System

Tooth, Ameloblast - Metaplasia, Squamous

    Narrative
    Normal ameloblasts (arrow) in a male B6C3F1 mouse from a chronic study.
    Normal ameloblasts (arrow) in a male B6C3F1 mouse from a chronic study.
    Tooth, Ameloblast - Metaplasia, Squamous in a male F344/N rat from a chronic study. The ameloblasts (compare with Figure 1) have been replaced by squamous epithelium (arrow).
    Tooth, Ameloblast - Metaplasia, Squamous in a male F344/N rat from a chronic study. The ameloblasts (compare with Figure 1) have been replaced by squamous epithelium (arrow).
    Normal ameloblasts (arrow) in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 1).
    Normal ameloblasts (arrow) in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 1).
    Tooth, Ameloblast - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 2). The ameloblasts (compare with Figure 3) have been replaced by squamous epithelium (arrow).
    Tooth, Ameloblast - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 2). The ameloblasts (compare with Figure 3) have been replaced by squamous epithelium (arrow).

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC