Nervous System

Spinal Cord, Dorsal Root Ganglion, Neuron - Vacuolation

    Normal appearance of rat dorsal root ganglionic neurons (cresyl violet). Image provided courtesy Dr. G. Krinke.
    Genuine dorsal root ganglionic vacuoles, appearing as variably sized, but generally large, clear vacuoles in the perikaryon of the affected neurons, may be accompanied by chromatolysis (arrow). Image provided courtesy Dr. G. Krinke.


    Peter Little, DVM, MS, PhD, DACVP
    Neuropathology Consultant
    Experimental Pathology Laboratories, Inc.  
    Research Triangle Park, NC

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC


    James P. Morrison, DVM, DACVP
    Scientific Director
    Charles River Laboratories, Pathology Associates
    Research Triangle Park, NC

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC