Musculoskeletal System

Bone - Increased Bone

    Narrative
    Bone - Increased bone in a female B6C3F1/N mouse from a chronic study. The medulla of this femur has been obliterated by increased amounts of bone.
    Bone - Increased bone in a female B6C3F1/N mouse from a chronic study. The medulla of this femur has been obliterated by increased amounts of bone.
    Bone - Increased bone in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There is a mix of mineralized and unmineralized bone in the medulla of the femur.
    Bone - Increased bone in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). There is a mix of mineralized and unmineralized bone in the medulla of the femur.
    Bone - Increased bone in a male B6C3F1/N mouse from a chronic study. The nasal turbinates are blunted and thickened.
    Bone - Increased bone in a male B6C3F1/N mouse from a chronic study. The nasal turbinates are blunted and thickened.
    Bone - Increased bone in a male Wistar Han rat from a chronic study. The bones of the nasal turbinates are thickened and fused together.
    Bone - Increased bone in a male Wistar Han rat from a chronic study. The bones of the nasal turbinates are thickened and fused together.

    Authors

    Mark J. Hoenerhoff, DVM, PhD, DACVP
    Associate Professor
    In Vivo Animal Core,Unit for Laboratory Animal Medicine
    University of Michigan
    Ann Arbor, MI

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Joel R. Leininger, DVM, PhD, DACVP
    JRL Consulting, LLC
    Chapel Hill, NC