Musculoskeletal System
Skeletal Muscle - Inflammation
Narrative
In NTP studies, there are five standard categories of inflammation: acute, suppurative, chronic, chronic-active, and granulomatous; abscesses are diagnosed as suppurative inflammation. In acute inflammation (Figure 1








Since inflammation can occur in response to, or result in, myofiber necrosis, myopathic changes in addition to edema and/or hemorrhage often occur concurrently. An inflammatory response is necessary to effectively repair damaged tissues; however, the nature, duration, and intensity of this response will crucially influence the overall outcome of repair.
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Skeletal muscle - Inflammation, Acute in a female Swiss CD-1 mouse from a chronic study. A neutrophilic infiltrate has led to necrosis and loss of muscle fibers.
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