Nervous System

Brain - Dysplasia

    Incidental hippocampal dysplasia in a female F344/N rat from a 2-year study. Note the abnormal undulation of the CA1 region (arrows) and the distortion of the dentate gyrus (arrowhead) compared with that in Figure 2.
    Normal hippocampus in a rat. Dentate gyrus is indicated by the arrowheads. Image provided courtesy Dr. D. Rao.


    Peter Little, DVM, MS, PhD, DACVP
    Neuropathology Consultant
    Experimental Pathology Laboratories, Inc.  
    Research Triangle Park, NC

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC


    James P. Morrison, DVM, DACVP
    Scientific Director
    Charles River Laboratories, Pathology Associates
    Research Triangle Park, NC

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC