Special Senses System

Harderian Gland - Atrophy

    Narrative
    Harderian gland - Atrophy in a female B6C3F1 mouse from a chronic study. The alveoli are shrunken, tortuous and lined by variably flattened epithelial cells (arrow), and there is concurrent interstitial fibrosis (arrowhead).
    Harderian gland - Atrophy in a female B6C3F1 mouse from a chronic study. The alveoli are shrunken, tortuous and lined by variably flattened epithelial cells (arrow), and there is concurrent interstitial fibrosis (arrowhead).
    Harderian gland - Atrophy in a female B6C3F1 mouse from a chronic study. Higher magnification showing the shrunken, tortuous acini with the variably flattened epithelial cells (arrow) and the interstitial fibrosis in more detail.
    Harderian gland - Atrophy in a female B6C3F1 mouse from a chronic study. Higher magnification showing the shrunken, tortuous acini with the variably flattened epithelial cells (arrow) and the interstitial fibrosis in more detail.

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC