Urinary System

Kidney, Renal Tubule - Necrosis

    Narrative
    Kidney, Renal tubule - Necrosis in a female B6C3F1 mouse from a chronic study. Diffuse tubule necrosis appears as lighter-staining, more eosinophilic tubules.
    Kidney, Renal tubule - Necrosis in a female B6C3F1 mouse from a chronic study. Diffuse tubule necrosis appears as lighter-staining, more eosinophilic tubules.
    Kidney, Renal tubule - Necrosis in a male B6C3F1 mouse from a subchronic study. Scattered tubular epithelial cell necrosis and sloughed necrotic epithelial cells are present.
    Kidney, Renal tubule - Necrosis in a male B6C3F1 mouse from a subchronic study. Scattered tubular epithelial cell necrosis and sloughed necrotic epithelial cells are present.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC