Urinary System

Kidney - Karyomegaly

    Narrative
    Kidney - Karyomegaly in a male B6C3F1 mouse from a chronic study. Numerous enlarged nuclei (karyomegaly) are present in the renal tubular epithelium.
    Kidney - Karyomegaly in a male B6C3F1 mouse from a chronic study. Numerous enlarged nuclei (karyomegaly) are present in the renal tubular epithelium.
    Kidney - Karyomegaly in a male F344/N rat from a subchronic study. Karyomegaly is present in several tubular epithelial cells.
    Kidney - Karyomegaly in a male F344/N rat from a subchronic study. Karyomegaly is present in several tubular epithelial cells.

    Authors 

    John Curtis Seely, DVM, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Kendall S. Frazier, DVM, PhD, DACVP, DABT
    Director, Cellular and Molecular Pathology, Safety Assessment
    GlaxoSmithKline
    King of Prussia, PA

    Gordon C. Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP
    Expert Consultant
    Tairua, New Zealand

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC