Immune System

Lymph Node - Extramedullary Hematopoiesis

    Narrative
    Lymph node - Extramedullary hematopoiesis in a female B6C3F1/N mouse from a chronic study. Increased numbers of hematopoietic cells are present within the lymph node medullary cords (arrows).
    Lymph node - Extramedullary hematopoiesis in a female B6C3F1/N mouse from a chronic study. Increased numbers of hematopoietic cells are present within the lymph node medullary cords (arrows).
    Lymph node - Extramedullary hematopoiesis in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Hematopoietic cells include erythroblasts (arrow), immature granulocytes (arrowhead), and megakaryocytes (asterisk).
    Lymph node - Extramedullary hematopoiesis in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Hematopoietic cells include erythroblasts (arrow), immature granulocytes (arrowhead), and megakaryocytes (asterisk).

    Authors

    Kristen Hobbie, DVM, PhD
    Principal Pathologist
    Huntingdon Life Sciences
    Peterborough, UK

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Holly M. Kolenda-Roberts, DVM, PhD, DACVP
    Veterinary Pathologist
    SNBL USA
    Everett, WA

    Reviewers

    Jerrold M. Ward, DVM, PhD, DACVP, FIATP
    Veterinary Pathologist
    Global VetPathology
    Montgomery Village, MD

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC