Nervous System

Brain - Pigment

    Narrative
    Pigment. A site of former hemorrhage (arrow) in the corpus callosum in a female F344/N rat from a chronic study. Multiple brown-pigmented hemosiderin-laden macrophages are present.
    Pigment. A site of former hemorrhage (arrow) in the corpus callosum in a female F344/N rat from a chronic study. Multiple brown-pigmented hemosiderin-laden macrophages are present.

    Authors 

    Peter Little, DVM, MS, PhD, DACVP
    Neuropathology Consultant
    Experimental Pathology Laboratories, Inc.  
    Research Triangle Park, NC

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    James P. Morrison, DVM, DACVP
    Scientific Director
    Charles River Laboratories, Pathology Associates
    Research Triangle Park, NC

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC