Alimentary System

Salivary Gland, Duct - Metaplasia, Squamous

    Narrative
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 1). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 1). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 3). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 3). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study. The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium (arrow).
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 5). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.
    Salivary gland, Duct - Metaplasia, Squamous in a male F344/N rat from a chronic study (higher magnification of Figure 5). The normally cuboidal ductal epithelial cells have been replaced by stratified squamous epithelium.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC