Alimentary System

Tooth - Necrosis

    Narrative
    Tooth - Necrosis in a male B6C3F1 mouse from a chronic study. There is necrosis of most components of the tooth, including the 2 denticles in the pulp (arrow), and suppurative inflammation of the tooth pulp (arrowhead).
    Tooth - Necrosis in a male B6C3F1 mouse from a chronic study. There is necrosis of most components of the tooth, including the 2 denticles in the pulp (arrow), and suppurative inflammation of the tooth pulp (arrowhead).
    Tooth - Necrosis in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 1). There is necrosis of all components of the tooth, including the 2 denticles in the pulp (arrow), and suppurative inflammation of the tooth pulp (arrowhead).
    Tooth - Necrosis in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 1). There is necrosis of all components of the tooth, including the 2 denticles in the pulp (arrow), and suppurative inflammation of the tooth pulp (arrowhead).

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC