Immune System

Lymph Node - Pigment

    Lymph node, Medullary sinuses - Pigment in a male Harlan Sprague-Dawley rat from a chronic study. Macrophages within the medullary sinuses contain intracytoplasmic golden-brown pigment suggestive of hemosiderin (arrows).
    Lymph node, Medullary cords - Pigment in a male F344/N rat from a chronic study. Macrophages within the medullary cords contain yellow-brown pigment suggestive of ceroid/lipofuscin (arrows).


    Kristen Hobbie, DVM, PhD
    Principal Pathologist
    Huntingdon Life Sciences
    Peterborough, UK

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Holly M. Kolenda-Roberts, DVM, PhD, DACVP
    Veterinary Pathologist
    Everett, WA


    Jerrold M. Ward, DVM, PhD, DACVP, FIATP
    Veterinary Pathologist
    Global VetPathology
    Montgomery Village, MD

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC