Reproductive System, Female

Ovary - Cyst

    Narrative
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study. The cyst is adjacent to a hematocyst (arrow), which contains blood.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study. The cyst is adjacent to a hematocyst (arrow), which contains blood.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). The cyst contains pale acellular eosinophilic follicular fluid and a thin outer wall lined by one or two layers of cuboidal or flattened granulosa cells.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). The cyst contains pale acellular eosinophilic follicular fluid and a thin outer wall lined by one or two layers of cuboidal or flattened granulosa cells.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study. The large cyst is the predominating feature of this ovary.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study. The large cyst is the predominating feature of this ovary.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Flattened epithelium lines the cyst wall, and flocculent eosinophilic material is present in the lumen.
    Ovary - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Flattened epithelium lines the cyst wall, and flocculent eosinophilic material is present in the lumen.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC