Cardiovascular System

Blood Vessel - Necrosis

    Narrative
    Mammary gland, Arteriole - Necrosis in a female F344/N rat from a subchronic study. Loss of cells in multiple arteriolar segments is apparent (arrows).
    Mammary gland, Arteriole - Necrosis in a female F344/N rat from a subchronic study. Loss of cells in multiple arteriolar segments is apparent (arrows).
    Mammary gland, Arteriole - Necrosis in a female F344/N rat from a subchronic study (higher magnification of Figure 1). Loss of cells and disorganization of the wall of multiple arteriolar segments is apparent (arrows).
    Mammary gland, Arteriole - Necrosis in a female F344/N rat from a subchronic study (higher magnification of Figure 1). Loss of cells and disorganization of the wall of multiple arteriolar segments is apparent (arrows).

    Authors:

    Crystal L. Johnson, DVM, DACVP
    Veterinary Pathologist II
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Paul W. Snyder, DVM, PhD, Diplomate ACVP, Fellow IATP
    Manager, EPL Midwest
    Senior Pathologist
    Experimental Pathology Laboratories, Inc. 
    West Lafayette, IN

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC